Recompensation in cirrhosis: unravelling the evolving natural history of nonalcoholic fatty liver disease

G Feng, L Valenti, VWS Wong, YM Fouad… - Nature Reviews …, 2024 - nature.com
Recompensation has gained increasing attention in the field of cirrhosis, particularly in
chronic liver disease with a definite aetiology. The current global prevalence of obesity and …

Impact of non-invasive biomarkers on hepatology practice: past, present and future

QM Anstee, L Castera, R Loomba - Journal of hepatology, 2022 - Elsevier
Over the last two decades, there have been tremendous advances in the non-invasive
diagnosis and risk stratification of chronic liver diseases (CLDs). Non-invasive approaches …

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis–2021 update

CPG Panel, A Berzigotti, E Tsochatzis, J Boursier… - Journal of …, 2021 - Elsevier
Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …

AASLD practice guidance on risk stratification and management of portal hypertension and varices in cirrhosis

DE Kaplan, C Ripoll, M Thiele, BE Fortune… - Hepatology, 2024 - journals.lww.com
This Practice Guidance from the American Association for the Study of Liver Disease
(AASLD) intends to coalesce best practice recommendations for the identification of portal …

Towards a new definition of decompensated cirrhosis

G D'Amico, M Bernardi, P Angeli - Journal of hepatology, 2022 - Elsevier
There is a universal agreement that the occurrence of clinical complications, such as ascites,
hepatic encephalopathy, gastrointestinal bleeding, and jaundice mark the transition from the …

[HTML][HTML] HCC risk stratification after cure of hepatitis C in patients with compensated advanced chronic liver disease

G Semmler, EL Meyer, K Kozbial, P Schwabl… - Journal of …, 2022 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC) is a major cause of morbidity and
mortality in patients with advanced chronic liver disease (ACLD) caused by chronic hepatitis …

[HTML][HTML] Clinical outcomes following DAA therapy in patients with HCV-related cirrhosis depend on disease severity

LAP Krassenburg, R Maan, A Ramji, MP Manns… - Journal of …, 2021 - Elsevier
Background & Aims HCV-infected patients with cirrhosis achieve high sustained virological
response (SVR) rates with direct-acting antivirals (DAAs) even after hepatic …

New clinical and pathophysiological perspectives defining the trajectory of cirrhosis

R Jalan, G D'Amico, J Trebicka, R Moreau, P Angeli… - Journal of …, 2021 - Elsevier
Traditionally, the complications of cirrhosis, namely variceal bleeding, ascites and hepatic
encephalopathy, were thought to result predominantly from circulatory dysfunction and …

Incidence of liver-and non-liver-related outcomes in patients with HCV-cirrhosis after SVR

R D'Ambrosio, E Degasperi, MP Anolli, I Fanetti… - Journal of …, 2022 - Elsevier
Background & Aims As the long-term benefits of a sustained virological response (SVR) in
HCV-related cirrhosis following direct-acting antiviral (DAA) treatment remain undefined, we …

Non-invasive tests for clinically significant portal hypertension after HCV cure

G Semmler, S Lens, EL Meyer, A Baiges… - Journal of …, 2022 - Elsevier
Background & Aims Non-invasive tests (NITs) for clinically significant portal hypertension
(CSPH; hepatic venous pressure gradient [HVPG]≥ 10 mmHg) have predominantly been …