Recompensation in cirrhosis: unravelling the evolving natural history of nonalcoholic fatty liver disease
Recompensation has gained increasing attention in the field of cirrhosis, particularly in
chronic liver disease with a definite aetiology. The current global prevalence of obesity and …
chronic liver disease with a definite aetiology. The current global prevalence of obesity and …
Impact of non-invasive biomarkers on hepatology practice: past, present and future
Over the last two decades, there have been tremendous advances in the non-invasive
diagnosis and risk stratification of chronic liver diseases (CLDs). Non-invasive approaches …
diagnosis and risk stratification of chronic liver diseases (CLDs). Non-invasive approaches …
EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis–2021 update
Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …
AASLD practice guidance on risk stratification and management of portal hypertension and varices in cirrhosis
DE Kaplan, C Ripoll, M Thiele, BE Fortune… - Hepatology, 2024 - journals.lww.com
This Practice Guidance from the American Association for the Study of Liver Disease
(AASLD) intends to coalesce best practice recommendations for the identification of portal …
(AASLD) intends to coalesce best practice recommendations for the identification of portal …
Towards a new definition of decompensated cirrhosis
G D'Amico, M Bernardi, P Angeli - Journal of hepatology, 2022 - Elsevier
There is a universal agreement that the occurrence of clinical complications, such as ascites,
hepatic encephalopathy, gastrointestinal bleeding, and jaundice mark the transition from the …
hepatic encephalopathy, gastrointestinal bleeding, and jaundice mark the transition from the …
[HTML][HTML] HCC risk stratification after cure of hepatitis C in patients with compensated advanced chronic liver disease
Background & Aims Hepatocellular carcinoma (HCC) is a major cause of morbidity and
mortality in patients with advanced chronic liver disease (ACLD) caused by chronic hepatitis …
mortality in patients with advanced chronic liver disease (ACLD) caused by chronic hepatitis …
[HTML][HTML] Clinical outcomes following DAA therapy in patients with HCV-related cirrhosis depend on disease severity
LAP Krassenburg, R Maan, A Ramji, MP Manns… - Journal of …, 2021 - Elsevier
Background & Aims HCV-infected patients with cirrhosis achieve high sustained virological
response (SVR) rates with direct-acting antivirals (DAAs) even after hepatic …
response (SVR) rates with direct-acting antivirals (DAAs) even after hepatic …
New clinical and pathophysiological perspectives defining the trajectory of cirrhosis
Traditionally, the complications of cirrhosis, namely variceal bleeding, ascites and hepatic
encephalopathy, were thought to result predominantly from circulatory dysfunction and …
encephalopathy, were thought to result predominantly from circulatory dysfunction and …
Incidence of liver-and non-liver-related outcomes in patients with HCV-cirrhosis after SVR
R D'Ambrosio, E Degasperi, MP Anolli, I Fanetti… - Journal of …, 2022 - Elsevier
Background & Aims As the long-term benefits of a sustained virological response (SVR) in
HCV-related cirrhosis following direct-acting antiviral (DAA) treatment remain undefined, we …
HCV-related cirrhosis following direct-acting antiviral (DAA) treatment remain undefined, we …
Non-invasive tests for clinically significant portal hypertension after HCV cure
G Semmler, S Lens, EL Meyer, A Baiges… - Journal of …, 2022 - Elsevier
Background & Aims Non-invasive tests (NITs) for clinically significant portal hypertension
(CSPH; hepatic venous pressure gradient [HVPG]≥ 10 mmHg) have predominantly been …
(CSPH; hepatic venous pressure gradient [HVPG]≥ 10 mmHg) have predominantly been …