Plasma lipolysis and changes in plasma and cerebrospinal fluid signaling lipids reveal abnormal lipid metabolism in chronic migraine

K Castor, J Dawlaty, X Arakaki, N Gross… - Frontiers in Molecular …, 2021 - frontiersin.org
Background Lipids are a primary storage form of energy and the source of inflammatory and
pain signaling molecules, yet knowledge of their importance in chronic migraine (CM) …

Generation of an immortalized astrocytic cell line from Abcd1-deficient H-2KbtsA58 mice to facilitate the study of the role of astrocytes in X-linked …

M Morita, A Toida, Y Horiuchi, S Watanabe… - Heliyon, 2021 - cell.com
Abstract X-linked adrenoleukodystrophy (X-ALD) is an inherited metabolic disease
characterized by inflammatory demyelination, and activated astrocytes as well as microglia …

Bone marrow transplantation into Abcd1‐deficient mice: Distribution of donor derived‐cells and biological characterization of the brain of the recipient mice

M Morita, T Kaizawa, T Yoda, T Oyama… - Journal of Inherited …, 2021 - Wiley Online Library
Abstract X‐linked adrenoleukodystrophy (X‐ALD) is a severe inherited metabolic disease
with cerebral inflammatory demyelination and abnormal accumulation of very long chain …

Therapeutic Strategies for X-Linked Adrenoleukodystrophy, a Representative Peroxisomal Disorder

M Morita - Peroxisomes: Biogenesis, Function, and Role in …, 2019 - Springer
Abstract X-linked adrenoleukodystrophy (X-ALD) is the most frequent peroxisomal disorder,
and is caused by dysfunction of the peroxisomal ABC protein ABCD1. X-ALD patients with …

Effect of Lorenzo's Oil on Hepatic Gene Expression and the Serum Fatty Acid Level in abcd1-Deficient Mice

M Morita, A Honda, A Kobayashi, Y Watanabe… - JIMD Reports, Volume …, 2018 - Springer
Lorenzo's oil is known to decrease the saturated very long chain fatty acid (VLCFA) level in
the plasma and skin fibroblasts of X-linked adrenoleukodystrophy (ALD) patients. However …

Inactivation génique des transporteurs ABC peroxysomaux ABCD1 et ABCD2 dans les cellules microgliales BV-2: étude de la physiopathogenèse de l' …

Q Raas - 2018 - theses.hal.science
L'adrénoleucodystrophie liée à l'X (X-ALD) est une maladie neurodégénérative sévère
caractérisée par une accumulation d'acides gras à très longue chaîne (AGTLC) …