[HTML][HTML] Benzimidazole and its derivatives: Recent Advances (2020–2022)

O Ebenezer, F Oyetunde-Joshua, OD Omotoso… - Results in …, 2023 - Elsevier
Benzimidazoles are fused heterocyclic ring systems containing two nitrogen atoms. They
have vital therapeutic significance in drug discovery. Many clinically approved drugs have …

Mechanisms of ferritinophagy and ferroptosis in diseases

S Li, P Huang, F Lai, T Zhang, J Guan, H Wan… - Molecular …, 2024 - Springer
The discovery of the role of autophagy, particularly the selective form like ferritinophagy, in
promoting cells to undergo ferroptosis has inspired us to investigate functional connections …

[PDF][PDF] Molecular mechanisms of melatonin-induced alleviation of synaptic dysfunction and neuroinflammation in Parkinson's disease: a review.

YL Guo, XJ Wei, T Zhang, T Sun - European Review for …, 2023 - europeanreview.org
Molecular mechanisms of melatonin-induced alleviation of synaptic dysfunction and
neuroinflammation in Parkinson’s disease: a Page 1 5070 Abstract. – This review focuses on …

[HTML][HTML] Targeting ferroptosis in neuroimmune and neurodegenerative disorders for the development of novel therapeutics

Z Li, Y Zhang, M Ji, C Wu, Y Zhang, S Ji - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Neuroimmune and neurodegenerative ailments impose a substantial societal burden.
Neuroimmune disorders involve the intricate regulatory interactions between the immune …

[HTML][HTML] Cycloartane Saponins from Astragalus glycyphyllos and Their In Vitro Neuroprotective, Antioxidant, and hMAO-B-Inhibiting Effects

I Stambolov, A Shkondrov, O Kunert, F Bucar… - Metabolites, 2023 - mdpi.com
Astragalus glycyphyllos (Fabaceae) is used in the traditional medicine of many countries
against hepatic and cardiac disorders. The plant contains mainly flavonoids and saponins …

[HTML][HTML] New Indole-3-Propionic Acid and 5-Methoxy-Indole Carboxylic Acid Derived Hydrazone Hybrids as Multifunctional Neuroprotectors

N Anastassova, D Stefanova, N Hristova-Avakumova… - Antioxidants, 2023 - mdpi.com
In light of the known neuroprotective properties of indole compounds and the promising
potential of hydrazone derivatives, two series of aldehyde-heterocyclic hybrids combining …

Design, synthesis and molecular docking studies of 5-fluoro 1-aryl/alkyl sulfonyl benzimidazole derivatives for treatment of Parkinson's disease

S Roy, S Sen, S Saha, SK Deb, B Singh… - … , Sulfur, and Silicon and …, 2023 - Taylor & Francis
Novel sulfonyl derivatives of 5-fluoro-substituted benzimidazole were synthesized and
characterized by 1H-NMR, 13C-NMR, 19F-NMR and mass spectrometry. Molecular docking …

Discovery of novel 2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivatives as multifunctional MAO-B inhibitors for the treatment of Parkinson's disease

Z Cao, X Wang, T Zhang, X Fu, F Zhang… - Journal of Enzyme …, 2023 - Taylor & Francis
To discover novel multifunctional agents for the treatment of Parkinson's disease, a series of
2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivatives was designed, synthesized …

Synthesis, Characterization, and MAO Inhibitory Activities of Three New Drug-like N-Acylhydrazone Derivatives

H TAŞCİ, T HÖKELEK, BN SAĞLIK, FB KAYNAK… - Journal of Molecular …, 2024 - Elsevier
In this study, three new N-acylhydrazone derivatives with the structural motif of N'-(
substitutedbenzylidene)-3-(5-methyl-2-benzoxazolinon-3-yl) propanehydrazide (5a-c) are …

Magnetic nanomaterials as green and recoverable nanocatalysts: Research on synthesis of benzimidazole derivatives

KM Batoo, M Kadhem Abid, AHM Hamoody… - Synthetic …, 2024 - Taylor & Francis
Research on benzimidazole derivatives is always an attractive challenge among synthetic
chemists because benzimidazole derivatives are very key and important components in the …