Malaria chemotherapeutics part I: History of antimalarial drug development, currently used therapeutics, and drugs in clinical development
M Schlitzer - ChemMedChem: Chemistry Enabling Drug …, 2007 - Wiley Online Library
Since ancient times, humankind has had to struggle against the persistent onslaught of
pathogenic microorganisms. Nowadays, malaria is still the most important infectious disease …
pathogenic microorganisms. Nowadays, malaria is still the most important infectious disease …
Retraction—Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis
several concerns were raised with respect to the veracity of the data and analyses
conducted by Surgisphere Corporation and its founder and our co-author, Sapan Desai, in …
conducted by Surgisphere Corporation and its founder and our co-author, Sapan Desai, in …
Mechanism of action, resistance, synergism, and clinical implications of azithromycin
M Heidary, A Ebrahimi Samangani… - Journal of Clinical …, 2022 - Wiley Online Library
Background Azithromycin (AZM), sold under the name Zithromax, is classified as a
macrolide. It has many benefits due to its immunomodulatory, anti‐inflammatory, and …
macrolide. It has many benefits due to its immunomodulatory, anti‐inflammatory, and …
[HTML][HTML] Systematic review and meta-analysis of the effectiveness and safety of hydroxychloroquine in treating COVID-19 patients
TH Yang, CY Chou, YF Yang, CS Chien… - Journal of the …, 2021 - journals.lww.com
Background: Since COVID-19 outbreak, hydroxychloroquine (HCQ) has been tested for
effective therapies, and the relevant researches have shown controversial results. Methods …
effective therapies, and the relevant researches have shown controversial results. Methods …
Targeting the liver stage of malaria parasites: a yet unmet goal
Malaria remains one of the world's most prevalent tropical diseases because of its high
mortality and morbidity burden, as well as its economic and social impacts on the …
mortality and morbidity burden, as well as its economic and social impacts on the …
Azithromycin for treating uncomplicated malaria
AM van Eijk, DJ Terlouw - Cochrane database of systematic …, 2011 - cochranelibrary.com
Background To prevent the development of drug resistance, the World Health Organization
(WHO) recommends treating malaria with combination therapy. Azithromycin, an antibiotic …
(WHO) recommends treating malaria with combination therapy. Azithromycin, an antibiotic …
Intermittent preventive treatment against malaria: an update
RD Gosling, ME Cairns, RM Chico… - Expert review of anti …, 2010 - Taylor & Francis
Intermittent preventive treatment (IPT) against malaria is a malaria control strategy aimed at
reducing the burden of malaria in certain high-risk groups, namely pregnant women and …
reducing the burden of malaria in certain high-risk groups, namely pregnant women and …
Hydroxychloroquine use and progression or prognosis of COVID-19: a systematic review and meta-analysis
Y Zang, X Han, M He, J Shi, Y Li - Naunyn-schmiedeberg's Archives of …, 2021 - Springer
Hydroxychloroquine (HCQ) has been implicated in antiviral activity in vitro against severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still controversy …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still controversy …
Macrolides and associated antibiotics based on similar mechanism of action like lincosamides in malaria
T Gaillard, J Dormoi, M Madamet, B Pradines - Malaria journal, 2016 - Springer
Malaria, a parasite vector-borne disease, is one of the biggest health threats in tropical
regions, despite the availability of malaria chemoprophylaxis. The emergence and rapid …
regions, despite the availability of malaria chemoprophylaxis. The emergence and rapid …
Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy
RM Chico, R Pittrof, B Greenwood, D Chandramohan - Malaria journal, 2008 - Springer
In the high malaria-transmission settings of sub-Saharan Africa, malaria in pregnancy is an
important cause of maternal, perinatal and neonatal morbidity. Intermittent preventive …
important cause of maternal, perinatal and neonatal morbidity. Intermittent preventive …