Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?

FG Teixeira, MM Carvalho, N Sousa… - Cellular and Molecular …, 2013 - Springer
The low regeneration potential of the central nervous system (CNS) represents a challenge
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …

Mesenchymal stem cells engineered for cancer therapy

K Shah - Advanced drug delivery reviews, 2012 - Elsevier
Recent pre-clinical and clinical studies have shown that stem cell-based therapies hold
tremendous promise for the treatment of human disease. Mesenchymal stem cells (MSC) …

Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and neurogenesis after cerebral ischemia in rats

L Wei, JL Fraser, ZY Lu, X Hu, SP Yu - Neurobiology of disease, 2012 - Elsevier
Hypoxic preconditioning of stem cells and neural progenitor cells has been tested for
promoting cell survival after transplantation. The present investigation examined the …

Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial

J Tan, W Wu, X Xu, L Liao, F Zheng, S Messinger… - Jama, 2012 - jamanetwork.com
Context Antibody-based induction therapy plus calcineurin inhibitors (CNIs) reduce acute
rejection rates in kidney recipients; however, opportunistic infections and toxic CNI effects …

Functional role of mesenchymal stem cells in the treatment of chronic neurodegenerative diseases

D Lo Furno, G Mannino… - Journal of cellular …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) can differentiate into not only cells of mesodermal
lineages, but also into endodermal and ectodermal derived elements, including neurons …

[HTML][HTML] The effect of hypoxia on mesenchymal stem cell biology

M Ejtehadifar, K Shamsasenjan… - Advanced …, 2015 - ncbi.nlm.nih.gov
Although physiological and pathological role of hypoxia have been appreciated in
mammalians for decades however the cellular biology of hypoxia more clarified in the past …

Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles to treat PCOS

HS Park, E Cetin, H Siblini, J Seok, H Alkelani… - International Journal of …, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is known as the most common endocrine disorder in
women. Previously, we suggested that human mesenchymal stem cells (MSCs) can reverse …

Mesenchymal Stem Cells Derived from Adipose Tissue vs Bone Marrow: In Vitro Comparison of Their Tropism towards Gliomas

C Pendleton, Q Li, DA Chesler, K Yuan… - PloS one, 2013 - journals.plos.org
Introduction Glioblastoma is the most common primary malignant brain tumor, and is
refractory to surgical resection, radiation, and chemotherapy. Human mesenchymal stem …

Phase I–II clinical trial assessing safety and efficacy of umbilical cord blood mononuclear cell transplant therapy of chronic complete spinal cord injury

H Zhu, W Poon, Y Liu, GKK Leung, Y Wong… - Cell …, 2016 - journals.sagepub.com
Umbilical cord blood-derived mononuclear cell (UCB-MNC) transplants improve recovery in
animal spinal cord injury (SCI) models. We transplanted UCB-MNCs into 28 patients with …

Management of achalasia: surgery or pneumatic dilation

JE Richter, GE Boeckxstaens - Gut, 2011 - gut.bmj.com
Achalasia is an esophageal motility disorder of unknown cause, characterised by
aperistalsis of the esophageal body and impaired lower esophageal sphincter relaxation …