Brain inflammation in epilepsy: experimental and clinical evidence

A Vezzani, T Granata - Epilepsia, 2005 - Wiley Online Library
Inflammatory reactions occur in the brain in various CNS diseases, including autoimmune,
neurodegenerative, and epileptic disorders. Proinflammatory and antiinflammatory cytokines …

Infantile spasms: little seizures, BIG consequences

WD Shields - Epilepsy Currents, 2006 - journals.sagepub.com
Infantile spasms is one of the “catastrophic childhood epilepsies” because of the difficulty in
controlling seizures and the association with mental retardation. However, early recognition …

Alternative epilepsy therapies: the ketogenic diet, immunoglobulins, and steroids

AN Prasad, CF Stafstrom, GL Holmes - Epilepsia, 1996 - Wiley Online Library
Despite the continued development and release of new antiepileptic drugs (AEDs), many
children have seizures that do not respond to conventional therapy or have related side …

Intravenous immunoglobulins in refractory childhood‐onset epilepsy: effects on seizure frequency, EEG activity, and cerebrospinal fluid cytokine profile

AD Billiau, P Witters, B Ceulemans, A Kasran… - …, 2007 - Wiley Online Library
Purpose: Several studies have reported favorable effects of intravenous immunoglobulins
(IVIG) in refractory epilepsy. Evidence substantiating an immunomodulatory action is scarce …

Immunological aspects of epilepsy

JA Aarli - Brain and Development, 1993 - Elsevier
Approximately 10% of patients with systemic lupus erythematosus (SLE) develop epileptic
seizures. When occurring before the onset of generalized SLE, the seizures are mainly …

The use of immunoglobulins in the treatment of human epilepsy

F Villani, G Avanzini - Neurological Sciences, 2002 - Springer
The use of immunoglobulin (IVIg) in intractable epilepsy is one of its oldest applications in
medicine, starting from the empirical observation of its beneficial effect on seizures. Immune …

High-dose intravenous immunoglobulin treatment in cryptogenic West and Lennox-Gastaut syndrome; an add-on study

BGM van Engelen, WO Renier, CMR Weemaes… - European journal of …, 1994 - Springer
In an add-on pilot study, a group of 15 children with cryptogenic and intractable West
syndrome (3) and Lennox-Gastaut syndrome (12) received intravenous immunoglobulin …

Intravenous immunoglobulin therapy in intractable childhood epilepsy: open-label study and review of the literature

MA Mikati, R Kurdi, Z El-Khoury, A Rahi, W Raad - Epilepsy & Behavior, 2010 - Elsevier
Our aim was to investigate the long term effectiveness of intravenous immunoglobulin (IVIG)
against intractable childhood epilepsy in the era of new antiepileptics and to determine the …

Inflammation in epileptic encephalopathies

O Shandra, SL Moshé, AS Galanopoulou - Advances in protein chemistry …, 2017 - Elsevier
West syndrome (WS) is an infantile epileptic encephalopathy that manifests with infantile
spasms (IS), hypsarrhythmia (in~ 60% of infants), and poor neurodevelopmental outcomes …

Intravenous immunoglobulins for epilepsy

JS Geng, JC Dong, Y Li, HJ Ni, K Jiang… - Cochrane Database …, 2019 - cochranelibrary.com
Background Epilepsy is a common neurological condition, with an estimated incidence of 50
per 100,000 persons. People with epilepsy may present with various types of immunological …