Chronic heart failure and comorbid renal dysfunction-a focus on type 2 cardiorenal syndrome

J Preeti, M Alexandre, I Pupalan… - Current Cardiology …, 2016 - ingentaconnect.com
The most important advancements in the Cardiorenal syndrome (CRS) are its definition and
subsequent classifications. When the predominant pathology and pathophysiology is the …

The wider considerations in closing chronic disease gaps–focus on heart failure and implementation

P Iyngkaran, C Hespe, F Hanna… - Current cardiology …, 2023 - ingentaconnect.com
Background: Heart failure (HF) is predominately a chronic disease. There are overlaps in HF
and chronic disease research and care. Chronic disease and HF research are conducted …

Burden from Study Questionnaire on Patient Fatigue in Qualitative Congestive Heart Failure Research

P Iyngkaran, W Usmani, Z Bahmani… - Journal of Cardiovascular …, 2024 - mdpi.com
Mixed methods research forms the backbone of translational research methodologies.
Qualitative research and subjective data lead to hypothesis generation and ideas that are …

[HTML][HTML] Risk stratification for coronary artery disease in multi-ethnic populations: Are there broader considerations for cost efficiency?

P Iyngkaran, W Chan, D Liew, J Zamani… - World journal of …, 2019 - ncbi.nlm.nih.gov
Coronary artery disease (CAD) screening and diagnosis are core cardiac specialty services.
From symptoms, autopsy correlations supported reductions in coronary blood flow and …

[PDF][PDF] Heart failure research paradigms using bedside observation on endothelial muscle common denominators to highlight important translational questions

P Iyngkaran, F Hanna, M De Courten… - Journal of Clinical and …, 2023 - jctres.com
ABSTRACT Background and Aim: Congestive heart failure (CHF) imposes a relevant
burden on healthcare systems, as it is associated with high morbidity and mortality rates and …

Heart Failure in Minority Populations-Impediments to Optimal Treatment in Australian Aborigines

P Iyngkaran, N Kangaharan, H Zimmet… - Current Cardiology …, 2016 - ingentaconnect.com
Chronic heart failure (CHF) among Aboriginal/Indigenous Australians is endemic. There are
also grave concerns for outcomes once acquired. This point is compounded by a lack of …

Exogenous cathepsin V protein protects human cardiomyocytes HCM from angiotensin Ⅱ-Induced hypertrophy

K Huang, L Gao, M Yang, J Wang, Z Wang… - … International Journal of …, 2017 - Elsevier
Angiotensin (Ang) Ⅱ-induced cardiac hypertrophy can deteriorate to heart failure, a leading
cause of mortality. Endogenous Cathepsin V (CTSV) has been reported to be …

Clinical impact of echocardiography parameters and molecular biomarkers in heart failure: Correlation of ACE2 and MCP‑1 polymorphisms with echocardiography …

M Suciu‑Petrescu, A Truta… - Experimental and …, 2021 - spandidos-publications.com
Heart failure is still the leading cause of hospitalization in patients over 65 years of age and
is defined as a multifactorial pathology which involves environmental factors and also …

Pharmacogenomics Informs Cardiovascular Pharmacotherapy

M Babayeva, B Azzi, ZG Loewy - Pharmacogenomics in Drug Discovery …, 2022 - Springer
Precision medicine exemplifies the emergence of personalized treatment options which may
benefit specific patient populations based upon their genetic makeup. Application of …

[HTML][HTML] Deciphering key genes in cardio-renal syndrome using network analysis

MM Ahmed, S Tazyeen, A Alam, A Farooqui, R Ali… - …, 2021 - ncbi.nlm.nih.gov
Cardio-renal syndrome (CRS) is a rapidly recognized clinical entity which refers to the
inextricably connection between heart and renal impairment, whereby abnormality to one …