[HTML][HTML] Recent advances in understanding the pathogenesis of rheumatoid arthritis: new treatment strategies

AL Mueller, Z Payandeh, N Mohammadkhani… - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

Immunomodulatory strategies for bone regeneration: a review from the perspective of disease types

N Su, C Villicana, F Yang - Biomaterials, 2022 - Elsevier
Tissue engineering strategies for treating bone loss to date have largely focused on
targeting stem cells or vascularization. Immune cells, including macrophages and T cells …

[HTML][HTML] Mesenchymal stem cell-based therapy for rheumatoid arthritis

M Sarsenova, A Issabekova, S Abisheva… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) have great potential to differentiate into various types of
cells, including but not limited to, adipocytes, chondrocytes and osteoblasts. In addition to …

[HTML][HTML] Role of reactive oxygen species and mitochondrial damage in rheumatoid arthritis and targeted drugs

W Jing, C Liu, C Su, L Liu, P Chen, X Li… - Frontiers in …, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …

[HTML][HTML] Human mesenchymal stem cell secretome driven T cell immunomodulation is IL-10 dependent

MT Shephard, MM Merkhan, NR Forsyth - International Journal of …, 2022 - mdpi.com
The Human Mesenchymal Stem Cell (hMSC) secretome has pleiotropic effects
underpinning its therapeutic potential. hMSC serum-free conditioned media (SFCM) …

[HTML][HTML] Apoptotic vesicles ameliorate lupus and arthritis via phosphatidylserine-mediated modulation of T cell receptor signaling

R Wang, M Hao, X Kou, B Sui, ML Sanmillan, X Zhang… - Bioactive Materials, 2023 - Elsevier
Mesenchymal stem cells (MSCs) influence T cells in health, disease and therapy through
messengers of intercellular communication including extracellular vesicles (EVs). Apoptosis …

Mesenchymal stromal cells for improvement of cardiac function following acute myocardial infarction: a matter of timing

S Barrère-Lemaire, A Vincent… - Physiological …, 2024 - journals.physiology.org
Acute myocardial infarction (AMI) is the leading cause of cardiovascular death and remains
the most common cause of heart failure. Reopening of the occluded artery, ie, reperfusion, is …

Mesenchymal stem cell–originated exosomal circular RNA circFBXW7 attenuates cell proliferation, migration and inflammation of fibroblast-like synoviocytes by …

L Chang, L Kan - Journal of Inflammation Research, 2021 - Taylor & Francis
Background Rheumatoid arthritis (RA) is a chronic autoimmune disease of articular joint
damage and elevated synovial hyperplasia. Abnormal proliferation, invasion inflammatory …

[HTML][HTML] Mesenchymal stem cell-originated exosomal lncRNA HAND2-AS1 impairs rheumatoid arthritis fibroblast-like synoviocyte activation through miR-143-3p …

Y Su, Y Liu, C Ma, C Guan, X Ma, S Meng - Journal of orthopaedic surgery …, 2021 - Springer
Background Long non-coding RNA heart and neural crest derivatives expressed 2-
antisense RNA 1 (HAND2-AS1) was found to be elevated in rheumatoid arthritis (RA) …

Mesenchymal stem cell suppresses the efficacy of CAR-T toward killing lymphoma cells by modulating the microenvironment through stanniocalcin-1

R Zhang, Q Liu, S Zhou, H He, M Zhao, W Ma - Elife, 2023 - elifesciences.org
Stem cells play critical roles both in the development of cancer and therapy resistance.
Although mesenchymal stem cells (MSCs) can actively migrate to tumor sites, their impact …