Evidence from the global outbreak of SARS-CoV-2 has clearly demonstrated that individuals
with pre-existing comorbidities are at a much greater risk of dying from COVID-19. This is of …

Aging is a biological process characterized by time-dependent functional declines that are
influenced by changes in redox status and by oxidative stress-induced inflammatory …

Objectives To evaluate health-related quality of life (HRQoL) in patients in different stages of
chronic kidney disease (CKD) up to initiation of dialysis treatment and to explore possible …

Chronic kidney disease (CKD) is known to involve inflammation, oxidative stress and
apoptosis. Here, we investigated the impact of curcumin (diferuloyl methane, a phenolic …

Phenoconversion transiently converts genotypic extensive metabolizers (EMs) into
phenotypic poor metabolizers (PMs) of drugs, potentially with corresponding changes in …

Inflammation and oxidative stress are known to be involved in the pathogenesis of chronic
kidney disease in humans, and in chronic renal failure (CRF) in rats. The aim of this work …

Abstract Kidney injury molecule-1 (KIM-1), a type l transmembrane glycoprotein, is
recognized as a potential biomarker for detection of tubular injury in the main renal …

Methods. The present study aimed to investigate the effect of nano-curcumin (120 mg) over
12 weeks on hs-CRP levels, adhesion molecules (ICAM-1, VCAM-1), and serum lipid …

The erectile dysfunction drug sildenafil has cardiopulmonary protective actions, and a
nephroprotective action in cisplatin and ischemia-reperfusion–induced acute kidney injury …

Acute kidney injury (AKI) is a critical care syndrome, resulting in acute reduction of renal
function and up to 22% mortality of hospitalized patients. Nerolidol is a major component in …