Recent progress in polysaccharides from Panax ginseng CA Meyer

M Guo, S Shao, D Wang, D Zhao, M Wang - Food & function, 2021 - pubs.rsc.org
Panax ginseng CA Meyer (P. ginseng) has a long history of medicinal use and can treat a
variety of diseases. P. ginseng contains a variety of active ingredients, such as saponins …

[HTML][HTML] The glucocorticoid receptor in cardiovascular health and disease

B Liu, TN Zhang, JK Knight, JE Goodwin - Cells, 2019 - mdpi.com
The glucocorticoid receptor is a member of the nuclear receptor family that controls many
distinct gene networks, governing various aspects of development, metabolism …

[HTML][HTML] Doxorubicin Induces Endotheliotoxicity and Mitochondrial Dysfunction via ROS/eNOS/NO Pathway

H He, L Wang, Y Qiao, Q Zhou, H Li, S Chen… - Frontiers in …, 2020 - frontiersin.org
Background: Doxorubicin (Dox) can induce endotheliotoxicity and damage the vascular
endothelium (VE). The most principle mechanism might be excess reactive oxygen species …

Panax ginseng against myocardial ischemia/reperfusion injury: A review of preclinical evidence and potential mechanisms

J Chen, Q Huang, J Li, Y Yao, W Sun, Z Zhang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Panax ginseng CA Meyer (P. ginseng) is effective in the
prevention and treatment of myocardial ischemia-reperfusion (I/R) injury. The mechanism by …

Anti-hypertensive and cardioprotective activities of traditional Chinese medicine-derived polysaccharides: A review

M Xie, W Tao, F Wu, K Wu, X Huang, G Ling… - International Journal of …, 2021 - Elsevier
Cardiovascular diseases (CVDs), a leading cause of death in modern society, have become
a major public health issue globally. Although numerous approaches have been proposed …

[HTML][HTML] A comprehensive assessment of apigenin as an antiproliferative, proapoptotic, antiangiogenic and immunomodulatory phytocompound

A Ghițu, A Schwiebs, HH Radeke, S Avram, I Zupko… - Nutrients, 2019 - mdpi.com
Apigenin (4′, 5, 7-trihydroxyflavone)(Api) is an important component of the human diet,
being distributed in a wide number of fruits, vegetables and herbs with the most important …

Multi-level fingerprinting and cardiomyocyte protection evaluation for comparing polysaccharides from six Panax herbal medicines

J Liu, F Yang, B Chen, X Li, Q Huang, J Li, X Li… - Carbohydrate …, 2022 - Elsevier
The role of polysaccharides in quality control of ginseng is underestimated. Large-scale
comparison on the polysaccharides of Panax ginseng (PG), P. quinquefolius (PQ), P …

[HTML][HTML] Integrating network analysis and experimental validation to reveal the mitophagy-associated mechanism of Yiqi Huoxue (YQHX) prescription in the treatment …

M Chen, G Zhong, M Liu, H He, J Zhou, J Chen… - Pharmacological …, 2023 - Elsevier
Myocardial ischemia/reperfusion (I/R) injury is the main cause of increasing postischemic
heart failure and currently there is no definite treatment for myocardial I/R injury. It has been …

Cardioprotective effect of the polysaccharide from Ophiopogon japonicus on isoproterenol-induced myocardial ischemia in rats

S Fan, J Zhang, Q Xiao, P Liu, Y Zhang, E Yao… - International journal of …, 2020 - Elsevier
Abstract The polysaccharide (OJP1), extracted from the root of Ophiopogon japonicus, is a
well-known traditional Chinese medicine used to treat cardiovascular diseases. The present …

[HTML][HTML] Capsaicin protects cardiomyocytes against lipopolysaccharide-induced damage via 14-3-3γ-mediated autophagy augmentation

Y Qiao, L Wang, T Hu, D Yin, H He, M He - Frontiers in pharmacology, 2021 - frontiersin.org
Background: The myocardium is susceptible to lipopolysaccharide (LPS)-induced damage
in sepsis, and cardiac dysfunction is a leading cause of mortality in patients with sepsis. The …