Emerging biomarkers for early detection of chronic kidney disease

M Mizdrak, M Kumrić, TT Kurir, J Božić - Journal of personalized …, 2022 - mdpi.com
Chronic kidney disease (CKD) is a major and serious global health problem that leads to
kidney damage as well as multiple systemic diseases. Early diagnosis and treatment are two …

[HTML][HTML] Unveiling the Dichotomy of Urinary Proteins: Diagnostic Insights into Breast and Prostate Cancer and Their Roles

Y Feng, Q Huo, BY Li, H Yokota - Proteomes, 2024 - mdpi.com
This review covers the diagnostic potential of urinary biomarkers, shedding light on their
linkage to cancer progression. Urinary biomarkers offer non-invasive avenues for detecting …

Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia

F Llorens, P Hermann, A Villar-Piqué… - Nature …, 2020 - nature.com
The clinical diagnosis of vascular dementia (VaD) is based on imaging criteria, and specific
biochemical markers are not available. Here, we investigated the potential of cerebrospinal …

Cadmium-induced kidney injury in mice is counteracted by a flavonoid-rich extract of bergamot juice, alone or in association with curcumin and resveratrol, via the …

S Cirmi, A Maugeri, A Micali, HR Marini, D Puzzolo… - Biomedicines, 2021 - mdpi.com
Cadmium (Cd) represents a public health risk due to its non-biodegradability and long
biological half-life. The main target of Cd is considered the kidney, where it accumulates. No …

Cordyceps militaris Improves Chronic Kidney Disease by Affecting TLR4/NF‐κB Redox Signaling Pathway

T Sun, W Dong, G Jiang, J Yang, J Liu… - Oxidative medicine …, 2019 - Wiley Online Library
Cordyceps militaris may show good promise in protecting against chronic kidney disease
(CKD) but the molecular mechanism remains unclear. CKD risk is associated with the Toll …

[HTML][HTML] Impaired nicotinamide adenine dinucleotide biosynthesis in the kidney of chronic kidney disease

X Liu, D Luo, S Huang, S Liu, B Zhang, F Wang… - Frontiers in …, 2021 - frontiersin.org
Chronic kidney disease (CKD) is a global public health problem with high morbidity and
mortality. Decreased nicotinamide adenine dinucleotide (NAD+) levels were found to be …

Lycopene ameliorates DEHP exposure-induced renal pyroptosis through the Nrf2/Keap-1/NLRP3/Caspase-1 axis

MZ Li, Y Zhao, XY Dai, M Talukder, JL Li - The Journal of Nutritional …, 2023 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is commonly used as a plasticizer in plastic
products, and due to its unique chemical composition, it frequently dissolves and enters the …

Plants with therapeutic potential for ischemic acute kidney injury: A systematic review

A Ali, T Lima Sampaio, H Khan… - Evidence‐Based …, 2022 - Wiley Online Library
Acute kidney injury (AKI) is a complex condition which has an intricate pathology mostly
involving hemodynamic, inflammatory, and direct toxic effects at the cellular level with high …

The potential use of near-and mid-infrared spectroscopy in kidney diseases

C Delrue, S De Bruyne, MM Speeckaert - International Journal of …, 2023 - mdpi.com
Traditional renal biomarkers such as serum creatinine and albuminuria/proteinuria are
rather insensitive since they change later in the course of the disease. In order to determine …

[HTML][HTML] Lipocalin-2 derived from adipose tissue mediates aldosterone-induced renal injury

WY Sun, B Bai, C Luo, K Yang, D Li, D Wu, M Félétou… - JCI insight, 2018 - ncbi.nlm.nih.gov
Lipocalin-2 is not only a sensitive biomarker, but it also contributes to the pathogenesis of
renal injuries. The present study demonstrates that adipose tissue–derived lipocalin-2 plays …