[HTML][HTML] The role of mitochondrial dysfunction in atrial fibrillation: translation to druggable target and biomarker discovery
L Pool, LFJM Wijdeveld, NMS de Groot… - International journal of …, 2021 - mdpi.com
Atrial fibrillation (AF) is the most prevalent and progressive cardiac arrhythmia worldwide
and is associated with serious complications such as heart failure and ischemic stroke …
and is associated with serious complications such as heart failure and ischemic stroke …
[HTML][HTML] NADPH oxidases and oxidative stress in the pathogenesis of atrial fibrillation
R Ramos-Mondragón, A Lozhkin, AE Vendrov… - Antioxidants, 2023 - mdpi.com
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and its prevalence
increases with age. The irregular and rapid contraction of the atria can lead to ineffective …
increases with age. The irregular and rapid contraction of the atria can lead to ineffective …
Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy …
F Seibertz, T Rubio, R Springer, F Popp… - Cardiovascular …, 2023 - academic.oup.com
Aims Atrial fibrillation (AF) is associated with tachycardia-induced cellular electrophysiology
alterations which promote AF chronification and treatment resistance. Development of novel …
alterations which promote AF chronification and treatment resistance. Development of novel …
Genetic and non-genetic risk factors associated with atrial fibrillation
Atrial fibrillation (AF) is the most common arrhythmic disorder and its prevalence in the
United States is projected to increase to more than twelve million cases in 2030. AF …
United States is projected to increase to more than twelve million cases in 2030. AF …
[HTML][HTML] Mitochondrial dysfunction in atrial fibrillation—Mechanisms and pharmacological interventions
P Muszyński, TA Bonda - Journal of Clinical Medicine, 2021 - mdpi.com
Despite the enormous progress in the treatment of atrial fibrillation, mainly with the use of
invasive techniques, many questions remain unanswered regarding the pathomechanism of …
invasive techniques, many questions remain unanswered regarding the pathomechanism of …
Oxidative stress: a bystander or a causal contributor to atrial remodelling and fibrillation?
D Dobrev, SC Dudley Jr - Cardiovascular Research, 2021 - academic.oup.com
This editorial refers to 'Inducibility, but not stability, of atrial fibrillation is increased by NOX2
overexpression in mice', by AS Mighiu et al., pp. 2354–2364. Despite enormous research …
overexpression in mice', by AS Mighiu et al., pp. 2354–2364. Despite enormous research …
Regions of highly recurrent electrogram morphology with low cycle length reflect substrate for atrial fibrillation
S Yoo, M Rottmann, J Ng, D Johnson, B Shanab… - Basic to Translational …, 2023 - jacc.org
Traditional anatomically guided ablation and attempts to perform electrogram-guided atrial
fibrillation (AF) ablation (CFAE, DF, and FIRM) have not been shown to be sufficient …
fibrillation (AF) ablation (CFAE, DF, and FIRM) have not been shown to be sufficient …
[HTML][HTML] LncRNA GAS5 Attenuates Cardiac Electrical Remodeling Induced by Rapid Pacing via the miR-27a-3p/HOXa10 Pathway
S Xi, H Wang, J Chen, T Gan, L Zhao - International Journal of Molecular …, 2023 - mdpi.com
Previous studies indicated long non-coding RNAs (lncRNAs) participated in the
pathogenesis of atrial fibrillation (AF). However, little is known about the role of lncRNAs in …
pathogenesis of atrial fibrillation (AF). However, little is known about the role of lncRNAs in …
[HTML][HTML] Research on atrial fibrillation mechanisms and prediction of therapeutic prospects: focus on the autonomic nervous system upstream pathways
J Huang, B Wu, P Qin, Y Cheng, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) is the most common clinical arrhythmia disorder. It can easily lead to
complications such as thromboembolism, palpitations, dizziness, angina, heart failure, and …
complications such as thromboembolism, palpitations, dizziness, angina, heart failure, and …
Nicotinamide adenosine dinucleotide phosphate oxidase-mediated signaling in cardiac remodeling
A Visnagri, RR Oexner… - Antioxidants & redox …, 2023 - liebertpub.com
Significance: Reactive oxygen species (ROS) play a key role in the pathogenesis of cardiac
remodeling and the subsequent progression to heart failure (HF). Nicotinamide adenosine …
remodeling and the subsequent progression to heart failure (HF). Nicotinamide adenosine …