Genetic load: genomic estimates and applications in non-model animals

G Bertorelle, F Raffini, M Bosse, C Bortoluzzi… - Nature Reviews …, 2022 - nature.com
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

[HTML][HTML] Rethinking fish biology and biotechnologies in the challenge era for burgeoning genome resources and strengthening food security

JF Gui, L Zhou, XY Li - Water Biology and Security, 2022 - Elsevier
Fish biology has been developed for more than 100 years, but some important
breakthroughs have been made in the last decade. Early studies commonly concentrated on …

Ensembl 2023

FJ Martin, MR Amode, A Aneja… - Nucleic acids …, 2023 - academic.oup.com
Abstract Ensembl (https://www. ensembl. org) has produced high-quality genomic resources
for vertebrates and model organisms for more than twenty years. During that time, our …

A multi-tissue atlas of regulatory variants in cattle

S Liu, Y Gao, O Canela-Xandri, S Wang, Y Yu, W Cai… - Nature …, 2022 - nature.com
Abstract Characterization of genetic regulatory variants acting on livestock gene expression
is essential for interpreting the molecular mechanisms underlying traits of economic value …

Bringing the animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services

ZL Hu, CA Park, JM Reecy - Nucleic acids research, 2022 - academic.oup.com
Abstract The Animal QTLdb (https://www. animalgenome. org/QTLdb) and CorrDB
(https://www. animalgenome. org/CorrDB) are unique resources for livestock animal …

Increases in extreme heat stress in domesticated livestock species during the twenty‐first century

P Thornton, G Nelson, D Mayberry… - Global Change …, 2021 - Wiley Online Library
Anthropogenic climate change is expected to have major impacts on domesticated livestock,
including increased heat stress in animals in both intensive and extensive livestock systems …

Functional annotations of three domestic animal genomes provide vital resources for comparative and agricultural research

C Kern, Y Wang, X Xu, Z Pan, M Halstead… - Nature …, 2021 - nature.com
Gene regulatory elements are central drivers of phenotypic variation and thus of critical
importance towards understanding the genetics of complex traits. The Functional Annotation …

Pig genome functional annotation enhances the biological interpretation of complex traits and human disease

Z Pan, Y Yao, H Yin, Z Cai, Y Wang, L Bai… - Nature …, 2021 - nature.com
The functional annotation of livestock genomes is crucial for understanding the molecular
mechanisms that underpin complex traits of economic importance, adaptive evolution and …

A compendium of genetic regulatory effects across pig tissues

J Teng, Y Gao, H Yin, Z Bai, S Liu, H Zeng… - Nature Genetics, 2024 - nature.com
Abstract The Farm Animal Genotype-Tissue Expression (FarmGTEx) project has been
established to develop a public resource of genetic regulatory variants in livestock, which is …

Single cell genomics as a transformative approach for aquaculture research and innovation

RR Daniels, RS Taylor, D Robledo… - Reviews in …, 2023 - Wiley Online Library
Single cell genomics encompasses a suite of rapidly maturing technologies that measure
the molecular profiles of individual cells within target samples. These approaches provide a …