Cancer cells undergo metabolic alterations to meet the immense demand for energy,
building blocks, and redox potential. Tumors show glucose-avid and lactate-secreting …

Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

The tumor microenvironment is proposed to contribute substantially to the progression of
cancers, including breast cancer. Cancer‐associated fibroblasts (CAFs) are the most …

Although Warburg's discovery of intensive glucose uptake by tumors, followed by lactate
fermentation in oxygen presence of oxygen was made a century ago, it is still an area of …

Cholesterol is a lipid molecule that plays an essential role in a number of biological
processes, both physiological and pathological. It is an essential structural constituent of cell …

Tumors have long been known to rewire their metabolism to endorse their proliferation,
growth, survival, and invasiveness. One of the common characteristics of these alterations is …

The constant changes in cancer cell bioenergetics are widely known as metabolic
reprogramming. Reprogramming is a process mediated by multiple factors, including …

Lactic acid is one of the most abundant products of cellular metabolism and has historically
been considered a cell-damaging metabolic product. However, as research has deepened …

In the current investigation, fifteen novel imidazole-pyridine-based molecules were
synthesized and tested against cell lines of the lung (H1299) and colon (HCT116) …

Simple Summary According to Globocan 2020 data, approximately 308,102 new cases of
brain cancer and central nervous system (CNS) cancers were reported worldwide, with …