Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal

L Wynants, B Van Calster, GS Collins, RD Riley… - bmj, 2020 - bmj.com
Objective To review and appraise the validity and usefulness of published and preprint
reports of prediction models for prognosis of patients with covid-19, and for detecting people …

Interleukin-6: obstacles to targeting a complex cytokine in critical illness

OJ McElvaney, GF Curley, S Rose-John… - The Lancet …, 2021 - thelancet.com
Circulating concentrations of the pleiotropic cytokine interleukin-6 (IL-6) are known to be
increased in pro-inflammatory critical care syndromes, such as sepsis and acute respiratory …

[PDF][PDF] IL-6 and IL-10 as predictors of disease severity in COVID-19 patients: results from meta-analysis and regression

SK Dhar, K Vishnupriyan, S Damodar, S Gujar, M Das - Heliyon, 2021 - cell.com
Abstract Aims SARS-CoV-2, an infectious agent behind the ongoing COVID-19 pandemic,
induces high levels of cytokines such as IL-1, IL-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ etc in …

[HTML][HTML] COVID-19 convalescent plasma composition and immunological effects in severe patients

Y Acosta-Ampudia, DM Monsalve, M Rojas… - Journal of …, 2021 - Elsevier
Convalescent plasma (CP) has emerged as a treatment for COVID-19. However, the
composition and mechanism of action are not fully known. Therefore, we undertook a two …

Vitamin D and its potential benefit for the COVID-19 pandemic

N Charoenngam, A Shirvani, MF Holick - Endocrine Practice, 2021 - Elsevier
Vitamin D is known not only for its importance for bone health but also for its biologic
activities on many other organ systems. This is due to the presence of the vitamin D receptor …

Attenuation of clinical and immunological outcomes during SARS‐CoV‐2 infection by ivermectin

GD de Melo, F Lazarini, F Larrous, L Feige… - EMBO molecular …, 2021 - embopress.org
The devastating pandemic due to SARS‐CoV‐2 and the emergence of antigenic variants
that jeopardize the efficacy of current vaccines create an urgent need for a comprehensive …

Long COVID in autoimmune rheumatic diseases

Y Fedorchenko, O Zimba - Rheumatology International, 2023 - Springer
Abstract Consequences of Corona Virus Disease-19 (COVID-19) in patients with rheumatic
diseases (RDs) are clinically diverse. SARS-CoV-2 infection has been associated with …

Clinical significance of measuring serum cytokine levels as inflammatory biomarkers in adult and pediatric COVID-19 cases: A review

BM Liu, TB Martins, LK Peterson, HR Hill - Cytokine, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a rapidly evolving infectious/inflammatory
disorder which has turned into a global pandemic. With severe acute respiratory syndrome …

Multiplexed, quantitative serological profiling of COVID-19 from blood by a point-of-care test

JT Heggestad, DS Kinnamon, LB Olson, J Liu… - Science …, 2021 - science.org
Highly sensitive, specific, and point-of-care (POC) serological assays are an essential tool to
manage coronavirus disease 2019 (COVID-19). Here, we report on a microfluidic POC test …

COVID-19 and the promise of small molecule therapeutics: Are there lessons to be learnt?

WS Ho, R Zhang, YL Tan, CLL Chai - Pharmacological Research, 2022 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic had grounded the world to a
standstill. As the disease continues to rage two years on, it is apparent that effective …