Analysis of gene expression and methylation datasets identified ADAMTS9, FKBP5, and PFKBF3 as biomarkers for osteoarthritis

ZF Li, RQ Zhang, XL Yang, DD Zhang… - Journal of cellular …, 2019 - Wiley Online Library
Background: Osteoarthritis (OA) is a kind of chronic osteoarthropathy and degenerative joint
disease. Epigenetic regulation in the gene expression dynamics has become increasingly …

Transcriptome analyses identify key genes and potential mechanisms in a rat model of osteoarthritis

HZ Li, HD Lu - Journal of Orthopaedic Surgery and Research, 2018 - Springer
Background Osteoarthritis (OA) is one of the most common degenerative diseases of the
joints worldwide, but still the pathogenesis of OA is largely unknown. The purpose of our …

Whole‐genome RNA sequencing identifies distinct transcriptomic profiles in impingement cartilage between patients with femoroacetabular impingement and hip …

BD Kuhns, JM Reuter, VL Hansen… - Journal of …, 2023 - Wiley Online Library
Femoroacetabular impingement (FAI) has a strong clinical association with the development
of hip osteoarthritis (OA); however, the pathobiological mechanisms underlying the transition …

[HTML][HTML] Integrated bioinformatics investigation of adenylyl cyclase family co-expression network in bladder cancer followed by preliminary validation of member 2 …

H Wang, W Luo, J Ji, M Qu, S Jiang… - Translational Cancer …, 2024 - ncbi.nlm.nih.gov
Background The adenylyl cyclase (ADCY) gene family encodes enzymes responsible for the
synthesis of cyclic adenosine monophosphate (cAMP) from adenosine triphosphate (ATP) …

Low expression of ADCY4 predicts worse survival of lung squamous cell carcinoma based on integrated analysis and immunohistochemical verification

Z Liu, L Ru, Z Ma - Frontiers in Oncology, 2021 - frontiersin.org
Purpose The molecular mechanism underlying the carcinogenesis and development of lung
squamous cell carcinoma (LUSC) has not been sufficiently elucidated. This analysis was …