[HTML][HTML] The NLRP3 inflammasome pathway: a review of mechanisms and inhibitors for the treatment of inflammatory diseases
The NLRP3 inflammasome is a multiprotein complex that plays a pivotal role in regulating
the innate immune system and inflammatory signaling. Upon activation by PAMPs and …
the innate immune system and inflammatory signaling. Upon activation by PAMPs and …
[HTML][HTML] Mold, mycotoxins and a dysregulated immune system: a combination of concern?
S Kraft, L Buchenauer, T Polte - International journal of molecular …, 2021 - mdpi.com
Fungi represent one of the most diverse and abundant eukaryotes on earth. The interplay
between mold exposure and the host immune system is still not fully elucidated. Literature …
between mold exposure and the host immune system is still not fully elucidated. Literature …
Ephedrae Herba polysaccharides inhibit the inflammation of ovalbumin induced asthma by regulating Th1/Th2 and Th17/Treg cell immune imbalance
B Zhang, M Zeng, Q Zhang, R Wang, J Jia, B Cao… - Molecular …, 2022 - Elsevier
Aims This study aimed to investigate the anti-asthma effects of Ephedrae Herba
polysaccharides (PE) and possible mechanisms related to immune inflammatory response …
polysaccharides (PE) and possible mechanisms related to immune inflammatory response …
[HTML][HTML] PM2. 5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice
R Xiong, W Jiang, N Li, B Liu, R He, B Wang… - … and environmental safety, 2021 - Elsevier
Abstract Fine particulate matter (PM2. 5) is one of the most important components of
environmental pollutants and is associated with lung injury. Pyroptosis, a form of …
environmental pollutants and is associated with lung injury. Pyroptosis, a form of …
[HTML][HTML] Qingwenzhike Prescription Alleviates Acute Lung Injury Induced by LPS via Inhibiting TLR4/NF-kB Pathway and NLRP3 Inflammasome Activation
C Zhang, X Wang, C Wang, C He, Q Ma, J Li… - Frontiers in …, 2021 - frontiersin.org
Background: Acute lung injury (ALI) is characterized by dysfunction of the alveolar epithelial
membrane caused by acute inflammation and tissue injury. Qingwenzhike (QWZK) …
membrane caused by acute inflammation and tissue injury. Qingwenzhike (QWZK) …
[HTML][HTML] Inhibition of the inflammasome activity of NLRP3 attenuates HDM-induced allergic asthma
M Ma, G Li, M Qi, W Jiang, R Zhou - Frontiers in immunology, 2021 - frontiersin.org
Inhaled allergens promote inflammatory response, tissue damage, and airway
hyperresponsiveness in the lungs, leading to allergic asthma. NLRP3, as an immune sensor …
hyperresponsiveness in the lungs, leading to allergic asthma. NLRP3, as an immune sensor …
[HTML][HTML] Dendritic cells: critical regulators of allergic asthma
I Morianos, M Semitekolou - International journal of molecular sciences, 2020 - mdpi.com
Allergic asthma is a chronic inflammatory disease of the airways characterized by airway
hyperresponsiveness (AHR), chronic airway inflammation, and excessive T helper (Th) type …
hyperresponsiveness (AHR), chronic airway inflammation, and excessive T helper (Th) type …
Activation of NLRP3 inflammasome contributes to the inflammatory response to allergic rhinitis via macrophage pyroptosis
H Zhou, W Zhang, D Qin, P Liu, W Fan, H Lv… - International …, 2022 - Elsevier
Objective Allergic rhinitis (AR) is a heterogeneous disease and its pathogenesis is still
unclear. Growing clinical evidence has thrown light on the key role of NOD-like Receptor …
unclear. Growing clinical evidence has thrown light on the key role of NOD-like Receptor …
Programmed cell death in asthma: apoptosis, autophagy, pyroptosis, ferroptosis, and necroptosis
L Liu, L Zhou, LL Wang, PD Zheng… - Journal of …, 2023 - Taylor & Francis
Bronchial asthma is a complex heterogeneous airway disease, which has emerged as a
global health issue. A comprehensive understanding of the different molecular mechanisms …
global health issue. A comprehensive understanding of the different molecular mechanisms …
[HTML][HTML] MUC1 attenuates neutrophilic airway inflammation in asthma by reducing NLRP3 inflammasome-mediated pyroptosis through the inhibition of the TLR4 …
L Liu, L Zhou, L Wang, Z Mao, P Zheng, F Zhang… - Respiratory …, 2023 - Springer
Background Neutrophilic airway inflammation is a challenge in asthma management and is
associated with poor patient prognosis. Mucin 1 (MUC1), which contains a cytoplasmic tail …
associated with poor patient prognosis. Mucin 1 (MUC1), which contains a cytoplasmic tail …