Humanized mice for immune system investigation: progress, promise and challenges

LD Shultz, MA Brehm, JV Garcia-Martinez… - Nature Reviews …, 2012 - nature.com
Significant advances in our understanding of the in vivo functions of human cells and tissues
and the human immune system have resulted from the development of'humanized'mouse …

Endotoxemia—menace, marker, or mistake?

RS Munford - Journal of Leucocyte Biology, 2016 - academic.oup.com
Endotoxemia is in its scientific ascendancy. Never has blood-borne, Gram-negative bacterial
endotoxin (LPS) been invoked in the pathogenesis of so many diseases—not only as a …

[HTML][HTML] Diagnostic value of presepsin for sepsis: a systematic review and meta-analysis

J Zhang, ZD Hu, J Song, J Shao - Medicine, 2015 - journals.lww.com
Diagnostic Value of Presepsin for Sepsis: A Systematic Revie... : Medicine Diagnostic Value of
Presepsin for Sepsis: A Systematic Review and Meta-Analysis : Medicine Log in or Register Get …

The human liver-uPA-SCID mouse: a model for the evaluation of antiviral compounds against HBV and HCV

P Meuleman, G Leroux-Roels - Antiviral research, 2008 - Elsevier
The study of the hepatitis B virus (HBV) and the hepatitis C virus (HCV) has long been
hampered by the lack of a suitable small animal model. Both viruses could only be studied in …

Markers of microbial translocation and risk of AIDS-related lymphoma

MA Marks, CS Rabkin, EA Engels, E Busch, W Kopp… - Aids, 2013 - journals.lww.com
Background: Depletion of gut-associated lymphocytes by HIV infection facilitates microbial
translocation, which may contribute to non-Hodgkin lymphoma (NHL) risk via chronic …

Potential cardiovascular disease risk markers among HIV-infected women initiating antiretroviral treatment

RC Kaplan, AL Landay, HN Hodis… - JAIDS Journal of …, 2012 - journals.lww.com
Background: Inflammation and hemostasis perturbation may be involved in vascular
complications of HIV infection. We examined atherogenic biomarkers and subclinical …

Chronic immune activation in common variable immunodeficiency (CVID) is associated with elevated serum levels of soluble CD14 and CD25 but not endotoxaemia

J Litzman, J Nechvátalová, J Xu, O Tichá… - Clinical & …, 2012 - academic.oup.com
Common variable immunodeficiency (CVID), the most frequent symptomatic
immunoglobulin primary immunodeficiency, is associated with chronic T cell activation and …

[HTML][HTML] Influence of dietary patterns on plasma soluble CD14, a surrogate marker of gut barrier dysfunction

FK Tabung, BM Birmann, MM Epstein… - Current developments in …, 2017 - Elsevier
Background Specific foods and nutrients, including alcohol, may contribute to gut barrier
dysfunction. However, to our knowledge, the influence of whole diets is currently unknown …

[HTML][HTML] Alternative cell sources for liver parenchyma repopulation: where do we stand?

T Tricot, J De Boeck, C Verfaillie - Cells, 2020 - mdpi.com
Acute and chronic liver failure is a highly prevalent medical condition with high morbidity
and mortality. Currently, the therapy is orthotopic liver transplantation. However, in some …

[HTML][HTML] Presepsin (scd14) as a marker of serious bacterial infections in chemotherapy induced severe neutropenia

E Olad, I Sedighi, A Mehrvar, M Tashvighi… - Iranian journal of …, 2014 - ncbi.nlm.nih.gov
Objective: Timely detection of serious bacterial infections or prediction of sepsis and death is
of paramount importance in neutropenic patients especially in oncology settings. The aim of …