The vascular endothelium is a dynamic, functionally complex organ, modulating multiple
biological processes, including vascular tone and permeability, inflammatory responses …

In obese individuals, atherogenic dyslipidemia is a very common and important factor in the
increased risk of cardiovascular disease. Adiposity-associated dyslipidemia is characterized …

Several prospective epidemiological studies have shown that there is a clear inverse
relationship between serum high-density lipoprotein-cholesterol (HDL-C) concentrations …

Atherosclerosis is a chronic progressive vascular disease. It starts early in life, has a long
asymptomatic phase, and a progression accelerated by various cardiovascular risk factors …

Even at low-density lipoprotein cholesterol (LDL-C) goal, patients with cardiometabolic
abnormalities remain at high risk of cardiovascular events. This paper aims (i) to critically …

Plasma high density lipoproteins (HDL) are small, dense, protein-rich particles compared
with other lipoprotein classes; roughly half of total HDL mass is accounted for by lipid …

HDL cholesterol activates endothelial cell production of the atheroprotective signaling
molecule NO, and it promotes endothelial repair. In this issue of the JCI, Besler et al. provide …

Nephrotic syndrome results in hyperlipidemia and profound alterations in lipid and
lipoprotein metabolism. Serum cholesterol, triglycerides, apolipoprotein B (apoB) …

For> 4 decades it has been recognized that elevated serum levels of high-density
lipoprotein cholesterol (HDL-C) are associated with reduced risk of cardiovascular disease …

Background—Endothelial dysfunction and injury are thought to play an important role in the
progression of coronary artery disease (CAD). High-density lipoprotein from healthy subjects …