Arachidonic acid is one of the most abundant and ubiquitous ω-6 polyunsaturated fatty acid,
present in esterified form in the membrane phospholipids of all mammalian cells and …

Antiplatelet therapy is the mainstay of treatment and secondary prevention of cardiovascular
disease (CVD), including acute coronary syndrome (ACS), transient ischemic attack (TIA) or …

Background Patients' responses to oral antiplatelet therapy are subject to variation. Bedside
monitoring offers the opportunity to improve outcomes after coronary stenting by …

Background—The optimal duration of dual-antiplatelet therapy and the risk-benefit ratio for
long-term dual-antiplatelet therapy after coronary stenting remain poorly defined. We …

Objective To assess the benefits and risks of short term (< 12 months) or extended (> 12
months) dual antiplatelet therapy (DAPT) versus standard 12 month therapy, following …

Background Optimum duration of dual antiplatelet treatment (DAPT) after coronary stenting
remains uncertain, with an unknown efficacy to safety ratio of extended treatment leading to …

Platelets play a fundamental role in normal hemostasis, while their inherited or acquired
dysfunctions are involved in a variety of bleeding disorders or thrombotic events. Several …

Context Clopidogrel pretreatment is recommended for patients with acute coronary
syndromes (ACS) and stable coronary artery disease who are scheduled for percutaneous …

Background: Immature platelets are less responsive to the effects of antiplatelet drugs and
contain messenger ribonucleic acid that is translationally active. They can be measured …

Aims The aim of this study was to compare on-thienopyridine platelet reactivity of elderly
patients (≥ 75 years) vs. younger patients (< 75 years). Elderly patients represent a growing …