Glioma infiltration and extracellular matrix: key players and modulators

VP Ferrer, V Moura Neto, R Mentlein - Glia, 2018 - Wiley Online Library
An outstanding characteristic of gliomas is their infiltration into brain parenchyma, a property
that impairs complete surgical resection; consequently, these tumors might recur, resulting in …

[HTML][HTML] Developmentally regulated signaling pathways in glioma invasion

S Mehta, C Lo Cascio - Cellular and Molecular Life Sciences, 2018 - Springer
Malignant gliomas are the most common, infiltrative, and lethal primary brain tumors
affecting the adult population. The grim prognosis for this disease is due to a combination of …

Molecular mechanisms of microRNAs in glioblastoma pathogenesis

AB Behrooz, H Latifi-Navid, A Nezhadi, M Świat… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Glioblastoma (GBM) is human's most prevalent and severe brain cancer. Epigenetic
regulators, micro (mi) RNAs, significantly impact cellular health and disease because of their …

Curcumin exhibits anti-tumor effect and attenuates cellular migration via Slit-2 mediated down-regulation of SDF-1 and CXCR4 in endometrial adenocarcinoma cells

VK Sirohi, P Popli, P Sankhwar, JB Kaushal… - The Journal of …, 2017 - Elsevier
Although curcumin shows anti-proliferative and anti-inflammatory activities in various
cancers, the effect of curcumin on cellular migration in endometrial adenocarcinoma cells …

SOX3 can promote the malignant behavior of glioblastoma cells

J Marjanovic Vicentic, D Drakulic, I Garcia, V Vukovic… - Cellular oncology, 2019 - Springer
Purpose Glioblastoma is the most common and lethal adult brain tumor. Despite current
therapeutic strategies, including surgery, radiation and chemotherapy, the median survival …

[HTML][HTML] Norepinephrine promotes glioma cell migration through up-regulating the expression of Twist1

X Wang, Y Wang, F Xie, ZT Song, ZQ Zhang, Y Zhao… - BMC cancer, 2022 - Springer
Background Glioma cells are characterized by high migration ability, resulting in aggressive
growth of the tumors and poor prognosis of patients. It has been reported that the stress …

Targeting gliomas: can a new alkylating hybrid compound make a difference?

R Pinheiro, C Braga, G Santos… - ACS Chemical …, 2017 - ACS Publications
Glioblastoma (GBM) is the most common and aggressive type of brain tumor in adults. The
triazene Temozolomide (TMZ), an alkylating drug, is the classical chemotherapeutic agent …

[HTML][HTML] Viscumins functionally modulate cell motility-associated gene expression

S Schötterl, M Hübner, A Armento… - International …, 2017 - spandidos-publications.com
Abstract In Europe extracts from Viscum album L., the European white-berry mistletoe, are
widely used as a complementary cancer therapy. Viscumins (mistletoe lectins, ML) have …

Molecular and clonal evolution in recurrent metastatic gliosarcoma

KJ Anderson, AC Tan… - Molecular …, 2020 - molecularcasestudies.cshlp.org
We discuss the molecular evolution of gliosarcoma, a mesenchymal type of glioblastoma
(GBM), using the case of a 37-yr-old woman who developed two recurrences and an …

Phosphatases and solid tumors: focus on glioblastoma initiation, progression and recurrences

M Dedobbeleer, E Willems, S Freeman… - Biochemical …, 2017 - portlandpress.com
Phosphatases and cancer have been related for many years now, as these enzymes
regulate key cellular functions, including cell survival, migration, differentiation and …