Immunobiology and pathogenesis of viral hepatitis

LG Guidotti, FV Chisari - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Among the many viruses that are known to infect the human liver, hepatitis B virus (HBV)
and hepatitis C virus (HCV) are unique because of their prodigious capacity to cause …

Hepatitis C virus: from entry to renal injury—facts and potentials

RS Barsoum - Nephrology Dialysis Transplantation, 2007 - academic.oup.com
In 1993, only 4 years after the discovery of HCV, three independent groups in Japan, Italy
and the US reported the detection of relevant viral markers of infection in patients with Type I …

Soluble serum CD81 is elevated in patients with chronic hepatitis C and correlates with alanine aminotransferase serum activity

MW Welker, D Reichert, S Susser, C Sarrazin… - PloS one, 2012 - journals.plos.org
Aim Cellular CD81 is a well characterized hepatitis C virus (HCV) entry factor, while the
relevance of soluble exosomal CD81 in HCV pathogenesis is poorly defined. We performed …

Monoclonal B cell lymphocytosis in hepatitis C virus infected individuals

C Fazi, A Dagklis, F Cottini, L Scarfo… - Cytometry Part B …, 2010 - Wiley Online Library
Background: Monoclonal B cell lymphocytosis (MBL) is a preclinical condition characterized
by an expansion of clonal B cells in the absence of B lymphocytosis (BALC< 5× 109/L) in the …

LincRNA01703 Facilitates CD81+ Exosome Secretion to Inhibit Lung Adenocarcinoma Metastasis via the Rab27a/SYTL1/CD81 Complex

Y Huang, S Guo, Y Lin, L Huo, H Yan, Z Lin, Z Chen… - Cancers, 2023 - mdpi.com
Simple Summary Metastasis, the hallmark of cancer, is accountable for about 90% of cancer-
related deaths. Long noncoding RNA (lncRNA), a subset of the noncoding RNAs, has …

Clinicopathologic characteristics and outcomes of transformed diffuse large B‐cell lymphoma in hepatitis C virus‐infected patients

J Hosry, RN Miranda, F Samaniego… - … journal of cancer, 2018 - Wiley Online Library
Hepatitis C virus (HCV) causes a chronic but curable infection associated with the
development of marginal zone lymphoma (MZL) and diffuse large B‐cell lymphoma …

A prospective study of T‐ and B‐lymphocyte subpopulations, CD81 expression levels on B cells and regulatory CD4+CD25+CD127low/−FoxP3+ T cells in patients …

B Soldevila, N Alonso… - Journal of viral …, 2011 - Wiley Online Library
Resolution of hepatitis C virus (HCV) infection requires a complex interplay between innate
and adaptative immune responses. The role of lymphocyte subpopulations during combined …

Infections, B cell receptor activation and autoimmunity: different check-point impairments lead to autoimmunity, clonal B cell expansion and fibrosis in different …

G Ferraccioli, B Tolusso - Autoimmunity reviews, 2007 - Elsevier
B cells as autoantibody producing cells are major players in several autoimmune chronic
inflammatory diseases (ACIDs). In some particular settings (ie Sjogren's syndrome …

Caveolin-1, tetraspanin CD81 and flotillins in lymphocyte cell membrane organization, signaling and immunopathology

AM Schaffer, S Minguet - Biochemical Society Transactions, 2020 - portlandpress.com
The adaptive immune system relies on B and T lymphocytes to ensure a specific and long-
lasting protection of an individual from a wide range of potential pathogenic hits …

[HTML][HTML] Increased CD5+ B-cells are associated with autoimmune phenomena in lepromatous leprosy patients

A Kotb, S Ismail, I Kimito, W Mohamed… - Journal of Infection and …, 2019 - Elsevier
Background and objective Leprosy is a chronic slowly progressive infection caused by
Mycobacterium leprae that primarily affects the skin and peripheral nerves. Lepromatous …