Over the last few decades, the prevalence of obesity has risen to epidemic proportions
worldwide. Consequently, the number of obesity in pregnancy has risen drastically …

The 'Developmental Origins of Health and Diseases' hypothesis posits that prenatal
maternal diet influences offspring growth and later life health outcomes. Dietary assessment …

Gestational diabetes is the most common medical complication in pregnancy. Historically,
gestational diabetes was considered a pregnancy complication involving treatment of rising …

Extracellular vesicles (EVs) are critical mediators of cell communication, playing important
roles in regulating molecular cross-talk between different metabolic tissues and influencing …

Gestational diabetes mellitus (GDM) is a disease of pregnancy that is associated with d-
glucose intolerance and foeto-placental vascular dysfunction. GMD causes mitochondrial …

Maternal diabetes and/or obesity in pregnancy are undoubtedly associated with later
disease-risk in the offspring. The placenta, interposed between the mother and the foetus, is …

Oxidative stress is the result of an imbalance between the formation of reactive oxygen
species (ROS) and the levels of enzymatic and non-enzymatic antioxidants. The assessment …

The placenta is a temporary organ with a unique structure and function to ensure healthy
fetal development. Placental dysfunction is involved in pre-eclampsia (PE), fetal growth …

Introduction Pregnant polycystic ovary syndrome (PCOS) patients are at increased risk for
myriad obstetric complications, with the placenta thought to play a key role in their …

Type 1 diabetes mellitus (T1DM) is associated with reduced fetal growth in early pregnancy,
but a contributing role of the placenta has remained elusive. Thus, we investigated whether …