Motile cilia are highly complex hair-like organelles of epithelial cells lining the surface of
various organ systems. Genetic mutations (usually with autosomal recessive inheritance) …

The core axoneme structure of both the motile cilium and sperm tail has the same
ultrastructural 9+ 2 microtubular arrangement. Thus, it can be expected that genetic defects …

Background Primary ciliary dyskinesia (PCD) is a motile ciliopathy characterised by
otosinopulmonary infections. Inheritance is commonly autosomal recessive, with extensive …

Primary ciliary dyskinesia (PCD) is a heterogeneous genetic condition. European and North
American diagnostic guidelines recommend transmission electron microscopy (TEM) as one …

Background Bronchiectasis can result from infectious, genetic, immunological and allergic
causes. 60–80% of cases are idiopathic, but a well-recognised genetic cause is the motile …

Primary ciliary dyskinesia (PCD) is a rare multiorgan disease caused by genetic mutations
resulting in defects in motile cilia. Because cilia are responsible for clearing the secretions …

Primary ciliary dyskinesia (PCD) is a genetically and clinically heterogeneous disease,
usually inherited in an autosomal recessive pattern. Patients with PCD develop recurrent …

Abstract Background and Objective Primary ciliary dyskinesia (PCD) is a rare genetic
disorder causing a defective ciliary structure, which predominantly leads to an impaired …

Primary Ciliary Dyskinesia (PCD) is a rare, under-recognized disease that affects respiratory
ciliary function, resulting in chronic oto-sino-pulmonary disease. The PCD clinical phenotype …

Primary ciliary dyskinesia (PCD) is an inherited cause of bronchiectasis. The estimated PCD
prevalence in children with bronchiectasis is up to 26% and in adults with bronchiectasis is 1 …