Control of sleep and wakefulness

RE Brown, R Basheer, JT McKenna… - Physiological …, 2012 - journals.physiology.org
This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …

Dreaming and the brain: toward a cognitive neuroscience of conscious states

JA Hobson, EF Pace-Schott… - Behavioral and brain …, 2000 - cambridge.org
Sleep researchers in different disciplines disagree about how fully dreaming can be
explained in terms of brain physiology. Debate has focused on whether REM sleep …

Adenosine: a mediator of the sleep-inducing effects of prolonged wakefulness

T Porkka-Heiskanen, RE Strecker, M Thakkar… - Science, 1997 - science.org
Both subjective and electroencephalographic arousal diminish as a function of the duration
of prior wakefulness. Data reported here suggest that the major criteria for a neural sleep …

Cholinergic, glutamatergic, and GABAergic neurons of the pedunculopontine tegmental nucleus have distinct effects on sleep/wake behavior in mice

D Kroeger, LL Ferrari, G Petit, CE Mahoney… - Journal of …, 2017 - Soc Neuroscience
The pedunculopontine tegmental (PPT) nucleus has long been implicated in the regulation
of cortical activity and behavioral states, including rapid eye-movement (REM) sleep. For …

Brainstem control of locomotion and muscle tone with special reference to the role of the mesopontine tegmentum and medullary reticulospinal systems

K Takakusaki, R Chiba, T Nozu, T Okumura - Journal of neural …, 2016 - Springer
The lateral part of the mesopontine tegmentum contains functionally important structures
involved in the control of posture and gait. Specifically, the mesencephalic locomotor region …

The neuropsychology of REM sleep dreaming

JA Hobson, R Stickgold, EF Pace-Schott - Neuroreport, 1998 - journals.lww.com
RECENT PET imaging and brain lesion studies in humans are integrated with new basic
research findings at the cellular level in animals to explain how the formal cognitive features …

Differential c-Fos expression in cholinergic, monoaminergic, and GABAergic cell groups of the pontomesencephalic tegmentum after paradoxical sleep deprivation …

KJ Maloney, L Mainville, BE Jones - Journal of Neuroscience, 1999 - Soc Neuroscience
Multiple lines of evidence indicate that neurons within the pontomesencephalic tegmentum
are critically involved in the generation of paradoxical sleep (PS). From single-unit recording …

Brainstem mechanisms of paradoxical (REM) sleep generation

PH Luppi, O Clement, E Sapin, C Peyron… - … -European Journal of …, 2012 - Springer
Paradoxical sleep (PS) is characterized by EEG activation with a disappearance of muscle
tone and the occurrence of rapid eye movements (REM) in contrast to slow-wave sleep …

Sleep apnea and quality of life

EH Yang, KM Hla, CA McHorney, T Havighurst… - Sleep, 2000 - academic.oup.com
Objective: To investigate the effects of sleep apnea (SA) on the quality of life (QOL). Design:
A prospective study of QOL in patients with and without SA as defined by an apnea …

On the Functional Significance of c-fos Induction During the Sleep-waking Cycle

C Cirelli, G Tononi - Sleep, 2000 - academic.oup.com
A striking finding in recent years has been that the transition from sleep to waking is
accompanied in many brain regions by a widespread activation of c-fos and other immediate …