The liver is the commonest site of metastatic disease for patients with colorectal cancer, with
at least 25% developing colorectal liver metastases (CRLM) during the course of their …

Liver metastasis is the commonest form of distant metastasis in colorectal cancer. Selection
criteria for surgery and liver-directed therapies have recently been extended. However …

Liver metastasis, the leading cause of colorectal cancer mortality, exhibits a highly
heterogeneous and suppressive immune microenvironment. Here, we sequenced 97 …

Background: Colorectal cancer (CRC) is one of the most common cancers all over the world,
but its epidemiology is obviously different in various regions. Methods: The treatment of CRC …

Colorectal carcinoma (CRC) is one of the leading causes of cancer-related deaths
worldwide, and up to 50% of patients with CRC develop colorectal liver metastases (CRLM) …

Background Decision making on optimal treatment strategy in patients with initially
unresectable colorectal cancer liver metastases (CRLM) remains complex because uniform …

Introduction Patients who recur in the first year after resection of colorectal liver metastases
(CRLM) do poorly. The aim of our study was to predict treatment failure in patients …

Background The use of neoadjuvant chemotherapy (NAC) in resectable colorectal liver
metastases (CRLM) patients is controversial. High-risk patients are more likely to benefit …

It has become clearer that advanced cancer, especially advanced breast cancer, is an
entirely displayed pathological system that is much more complex than previously …

BACKGROUND In recent years, neoadjuvant chemotherapy (NAC) has been increasingly
used in patients with resectable colorectal liver metastases. However, the efficacy and safety …