Inflammatory microenvironment-targeted nanotherapies

G Zhang, L Ma, L Bai, M Li, T Guo, B Tian, Z He… - Journal of Controlled …, 2021 - Elsevier
Inflammatory microenvironments (IMEs) are common pathological characteristics and drive
the development of multiple chronic diseases. Thus, IME-targeted therapies exhibit potential …

Multifunctional and biodegradable methacrylated gelatin/Aloe vera nanofibers for endodontic disinfection and immunomodulation

SS Namazi, AH Mahmoud, R Dal-Fabbro, Y Han… - Biomaterials …, 2023 - Elsevier
Currently employed approaches and materials used for vital pulp therapies (VPTs) and
regenerative endodontic procedures (REPs) lack the efficacy to predictably achieve …

Platform technologies for regenerative endodontics from multifunctional biomaterials to tooth-on-a-chip strategies

DG Soares, EAF Bordini, WB Swanson… - Clinical oral …, 2021 - Springer
Objectives The aim of this review is to highlight recent progress in the field of biomaterials-
mediated dental pulp tissue engineering. Specifically, we aim to underscore the critical …

A versatile GelMA composite hydrogel: Designing principles, delivery forms and biomedical applications

Y Zhang, J Lv, J Zhao, G Ling, P Zhang - European Polymer Journal, 2023 - Elsevier
Gelatin methacryloyl (GelMA), a kind of modified biomaterials with adjustable degradability
from gelatin, can composite with various composite materials and therapeutic substances …

Preparation, thermal response mechanisms and biomedical applications of thermosensitive hydrogels for drug delivery

J Luo, X Zhao, B Guo, Y Han - Expert Opinion on Drug Delivery, 2023 - Taylor & Francis
Introduction Drug treatment is one of the main ways of coping with disease today. For the
disadvantages of drug management, thermosensitive hydrogel is used as a …

Injectable multifunctional drug delivery system for hard tissue regeneration under inflammatory microenvironments

EAF Bordini, JA Ferreira, N Dubey… - ACS Applied Bio …, 2021 - ACS Publications
Engineering multifunctional hydrogel systems capable of amplifying the regenerative
capacity of endogenous progenitor cells via localized presentation of therapeutics under …

Recent advancements in hydrogels as novel tissue engineering scaffolds for dental pulp regeneration

X Guo, J Li, Y Wu, L Xu - International Journal of Biological Macromolecules, 2024 - Elsevier
Although conventional root canal treatment offers an effective therapeutic solution, it
negatively affects the viability of the affected tooth. In recent years, pulp regeneration …

An inflammation-responsive double-layer microneedle patch for recurrent atopic dermatitis therapy

L Song, J Chi, Z Li, Y Tao, Y Sun, Q Zhou, S Lu… - International Journal of …, 2023 - Elsevier
Seeking a potent therapeutic strategy for alleviating atopic dermatitis (AD) attack and
preventing its recurrence is highly desired but remains challenging in clinical practice. Here …

[HTML][HTML] Strategies of functionalized GelMA-based bioinks for bone regeneration: Recent advances and future perspectives

Y Zhu, X Yu, H Liu, J Li, M Gholipourmalekabadi, K Lin… - Bioactive Materials, 2024 - Elsevier
Gelatin methacryloyl (GelMA) hydrogels is a widely used bioink because of its good
biological properties and tunable physicochemical properties, which has been widely used …

Engineering of injectable antibiotic-laden fibrous microparticles gelatin methacryloyl hydrogel for endodontic infection ablation

JS Ribeiro, EA Münchow, EAF Bordini… - International Journal of …, 2022 - mdpi.com
This study aimed at engineering cytocompatible and injectable antibiotic-laden fibrous
microparticles gelatin methacryloyl (GelMA) hydrogels for endodontic infection ablation …