[HTML][HTML] Current understanding of hexavalent chromium [Cr (VI)] neurotoxicity and new perspectives

JP Wise Jr, JL Young, J Cai, L Cai - Environment international, 2022 - Elsevier
Abstract Hexavalent chromium [Cr (VI)] is a global environmental pollutant that increases
risk for several types of cancers and is increasingly being recognized as a neurotoxicant …

[HTML][HTML] Study on detoxification and removal mechanisms of hexavalent chromium by microorganisms

X Tang, Y Huang, Y Li, L Wang, X Pei, D Zhou… - Ecotoxicology and …, 2021 - Elsevier
Extensive industrial activities have led to an increase of the content of chromium in the
environment, which causes serious pollution to the surrounding water, soil and atmosphere …

Molecular and epigenetic mechanisms of Cr (VI)-induced carcinogenesis

QY Chen, A Murphy, H Sun, M Costa - Toxicology and applied …, 2019 - Elsevier
Chromium (Cr) is a naturally occurring metallic element found in the Earth's crust. While
trivalent chromium ([Cr (III)] is considered non-carcinogenic, hexavalent chromium [Cr (VI)] …

miRNA dysregulation is an emerging modulator of genomic instability

APF Cardoso, M Banerjee, AN Nail, A Lykoudi… - Seminars in cancer …, 2021 - Elsevier
Genomic instability consists of a range of genetic alterations within the genome that
contributes to tumor heterogeneity and drug resistance. It is a well-established characteristic …

Airborne particulate matter induces oxidative damage, DNA adduct formation and alterations in DNA repair pathways

EM Quezada-Maldonado, Y Sánchez-Pérez… - Environmental …, 2021 - Elsevier
Air pollution, which includes particulate matter (PM), is classified in group 1 as a carcinogen
to humans by the International Agency for Research in Cancer. Specifically, PM exposure …

Cr (VI)-induced methylation and down-regulation of DNA repair genes and its association with markers of genetic damage in workers and 16HBE cells

G Hu, P Li, X Cui, Y Li, J Zhang, X Zhai, S Yu… - Environmental …, 2018 - Elsevier
To examine the mechanism of hexavalent chromium [Cr (VI)]-induced carcinogenesis, a
cross-sectional study in workers with or without exposure to Cr (VI) as well as in vitro …

The crosstalk between trace elements with DNA damage response, repair, and oxidative stress in cancer

S Samavarchi Tehrani… - Journal of cellular …, 2019 - Wiley Online Library
DNA damage response (DDR) is a regulatory system responsible for maintaining genome
integrity and stability, which can sense and transduce DNA damage signals. The severity of …

Hexavalent chromium–induced chromosome instability drives permanent and heritable numerical and structural changes and a DNA repair–deficient phenotype

SS Wise, AEM Aboueissa, J Martino, JP Wise Sr - Cancer research, 2018 - AACR
A key hypothesis for how hexavalent chromium [Cr (VI)] causes cancer is that it drives
chromosome instability (CIN), which leads to neoplastic transformation. Studies show …

[HTML][HTML] Progress on the impact of persistent pollutants on marine turtles: a review

M Arienzo - Journal of Marine Science and Engineering, 2023 - mdpi.com
The review examines the most recent advances on the effect of persistent pollutants on sea
turtles. Research on this topic is still limited, especially that related to toxicity, since they are …

Molecular mechanisms linking environmental toxicants to cancer development: Significance for protective interventions with polyphenols

R Lagoa, D Marques-da-Silva, M Diniz, M Daglia… - Seminars in Cancer …, 2022 - Elsevier
Human exposure to environmental toxicants with diverse mechanisms of action is a growing
concern. In addition to well-recognized carcinogens, various chemicals in environmental …