Recent advances of ocular drug delivery systems: prominence of ocular implants for chronic eye diseases

M Mostafa, A Al Fatease, RG Alany, H Abdelkader - Pharmaceutics, 2023 - mdpi.com
Chronic ocular diseases can seriously impact the eyes and could potentially result in
blindness or serious vision loss. According to the most recent data from the WHO, there are …

Cubosomes: An Emerging Nanodrug delivery Platform for Anti-Diabetic Medications

SS Garg, A Vyas, V Kirthi, J Gupta - Journal of Drug Delivery Science and …, 2024 - Elsevier
Cubosomes are nanostructured particles characterized by a crystalline lyotropic liquid core
that can be formulated by amphiphilic lipids with the capability of natural self-assembly in …

[HTML][HTML] Potential application of sucrose acetate isobutyrate, and glyceryl monooleate for nanonization and bioavailability enhancement of rivaroxaban tablets

AA Al-Shoubki, MH Teaima, R Abdelmonem… - Pharmaceutical Science …, 2024 - Elsevier
This study aimed to investigate the use of Sucrose acetate isobutyrate (SAIB) and Glyceryl
monooleate (GMO) as co-formers for creating Cubosomes and SAIB-based nanodispersions …

Magnetic targeting of lornoxicam/SPION bilosomes loaded in a thermosensitive in situ hydrogel system for the management of osteoarthritis: Optimization, in vitro, ex …

B Ibrahiem, R Shamma, A Salama, H Refai - Drug Delivery and …, 2023 - Springer
Osteoarthritis is a bone and joint condition characterized pathologically by articular cartilage
degenerative damage and can develop into a devastating and permanently disabling …

Limonene-Enriched Ultra-Structural Cubosomes to Augment Ocular Delivery of a Poorly Water Soluble Anti-Fungal Drug: Fabrication, Characterization, Statistical …

AA Nemr, S Ahmed, IM Adel - Journal of Drug Delivery Science and …, 2024 - Elsevier
The target of this investigation was to obtain the composition of the optimized Fenticonazole
nitrate (FCN)-loaded cubosomal formula that can prolong precorneal retention, increase …

Radiation Synthesis and Characterization of pH-Responsive Sodium Alginate/Poly (acrylic acid) Nanogel Loaded with Ferulic Acid for Anticancer Drug Delivery

K El-Adl, MM Ghobashy, AFM Ismail, A El-morsy… - Materials Chemistry and …, 2024 - Elsevier
This study focuses on the synthesis and characterization of a pH-responsive nanogel system
composed of sodium alginate (NaAlg) and poly (acrylic acid) loaded with ferulic acid. The …

Verapamil-Loaded Cubosomes for Enhancing Intranasal Drug Delivery: Development, Characterization, Ex Vivo Permeation, and Brain Biodistribution Studies

MM Faisal, E Gomaa, AE Ibrahim, S El Deeb… - AAPS …, 2024 - Springer
Verapamil hydrochloride (VRP), an antihypertensive calcium channel blocker drug has
limited bioavailability and short half-life when taken orally. The present study was aimed at …

Optimizing Nimesulide Loaded Cubosomal Gel for Enhanced Efficacy: A Systematic Engineering Approach with Factorial Design for Topical Applications

V Deshmukh, YV Pore, R Shikalgar… - Journal of …, 2024 - Springer
Purpose The primary aim of this study is to develop a cubosome nanoformulation for the
optimized delivery of nimesulide, with a focus on improving its efficacy and reducing adverse …

Perspective use of bio-adhesive liquid crystals as ophthalmic drug delivery systems

M Tarsitano, A Mancuso, MC Cristiano, K Urbanek… - Scientific Reports, 2023 - nature.com
The success of many drugs in ophthalmic treatments is hindered by their physico-chemical
properties and the limited precorneal retention time. Here, lyotropic liquid crystals are …

[PDF][PDF] Cubosome-based Corticosteroidal Drug Delivery System for Sustained Ocular Delivery: A Pharmacokinetic Investigation

SS Chakorkar, JASG Mulla - Ind. J. Pharm. Edu. Res, 2024 - ijper.org
Background: Fluorometholone is an anti-inflammatory glucocorticoid. It has been used in
various ocular inflammatory as well as infectious conditions. Opting for sustained release in …