Highly processed foods can be considered addictive substances based on established scientific criteria
AN Gearhardt, AG DiFeliceantonio - Addiction, 2023 - Wiley Online Library
Background There is growing evidence that an addictive‐eating phenotype may exist. There
is significant debate regarding whether highly processed foods (HPFs; foods with refined …
is significant debate regarding whether highly processed foods (HPFs; foods with refined …
Dopamine circuit mechanisms of addiction-like behaviors
CL Poisson, L Engel, BT Saunders - Frontiers in Neural Circuits, 2021 - frontiersin.org
Addiction is a complex disease that impacts millions of people around the world. Clinically,
addiction is formalized as substance use disorder (SUD), with three primary symptom …
addiction is formalized as substance use disorder (SUD), with three primary symptom …
Novelty-induced locomotor behavior predicts heroin addiction vulnerability in male, but not female, rats
BN Kuhn, N Cannella, AD Crow, AT Roberts… - …, 2022 - Springer
Rationale The ongoing rise in opioid use disorder (OUD) has made it imperative to better
model the individual variation within the human population that contributes to OUD …
model the individual variation within the human population that contributes to OUD …
Environmental enrichment promotes adaptive responding during tests of behavioral regulation in male heterogeneous stock rats
Organisms must regulate their behavior flexibly in the face of environmental challenges.
Failure can lead to a host of maladaptive behavioral traits associated with a range of …
Failure can lead to a host of maladaptive behavioral traits associated with a range of …
Genome-wide association study on three behaviors tested in an open field in heterogeneous stock rats identifies multiple loci implicated in psychiatric disorders
Many personality traits are influenced by genetic factors. Rodents models provide an
efficient system for analyzing genetic contribution to these traits. Using 1,246 adolescent …
efficient system for analyzing genetic contribution to these traits. Using 1,246 adolescent …
Effects of two kinds of noradrenergic ADHD medicines on sign-tracking and goal-tracking in male rats.
JM Holden - Experimental and Clinical Psychopharmacology, 2022 - psycnet.apa.org
Sign-and goal-tracking are behaviors seen in many species when a conditioned stimulus
and it's corresponding unconditioned stimulus are presented at separate locations, and …
and it's corresponding unconditioned stimulus are presented at separate locations, and …
Effects of bupropion on sign-and goal-tracking in male Sprague Dawley rats
JM Holden - Behavioural Brain Research, 2023 - Elsevier
Relapse into addiction is often triggered by cues that have a Pavlovian association with
drugs and drug-taking. Sign-tracking involves approach of and interaction with Pavlovian …
drugs and drug-taking. Sign-tracking involves approach of and interaction with Pavlovian …
Dextromethorphan reduces sign-tracking but not goal-tracking in male Sprague-Dawley rats
JM Holden, A Salem - Neurobiology of Learning and Memory, 2022 - Elsevier
Sign-tracking is a well-known phenomenon in appetitive Pavlovian conditioning in which
subjects approach the site of a conditioned stimulus (CS) associated with an appetitive …
subjects approach the site of a conditioned stimulus (CS) associated with an appetitive …
Effects of three serotonin reuptake inhibitors on sign-tracking in male Sprague-Dawley rats
JM Holden - Physiology & Behavior, 2023 - Elsevier
Sign-tracking is a behavior with relevance to cue-triggered relapse addiction, a Pavlovian
conditioned approach behavior directed at the conditioned stimulus. The study examined …
conditioned approach behavior directed at the conditioned stimulus. The study examined …
Acute MK-801 increases measures of both sign-tracking and goal-tracking in male Sprague-Dawley rats
JM Holden, A Barbaro, K Azure, M Arth - Pharmacology Biochemistry and …, 2024 - Elsevier
Sign-tracking is a Pavlovian conditioned approach behavior thought to be important in
understanding cue-driven relapse to drug use, and strategies for reducing sign-tracking may …
understanding cue-driven relapse to drug use, and strategies for reducing sign-tracking may …