Nrf2/HO-1 signaling stimulation through acetyl-11-keto-beta-boswellic acid (AKBA) provides neuroprotection in ethidium bromide-induced experimental model of …
Multiple sclerosis (MS) is a severe immune-mediated neurological disease characterized by
neuroinflammation, demyelination, and axonal degeneration in the central nervous system …
neuroinflammation, demyelination, and axonal degeneration in the central nervous system …
Activation of IGF-1/GLP-1 signalling via 4-hydroxyisoleucine prevents motor neuron impairments in experimental ALS-rats exposed to methylmercury-induced …
Amyotrophic lateral sclerosis (ALS) is a severe adult motor neuron disease that causes
progressive neuromuscular atrophy, muscle wasting, weakness, and depressive-like …
progressive neuromuscular atrophy, muscle wasting, weakness, and depressive-like …
Acetyl-11-keto-beta boswellic acid (AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive …
Obsessive-Compulsive disorder (OCD) is a long-term and persistent mental illness
characterised by obsessive thoughts and compulsive behaviours. Numerous factors can …
characterised by obsessive thoughts and compulsive behaviours. Numerous factors can …
Neuroprotective effect of chrysophanol as a PI3K/AKT/mTOR signaling inhibitor in an experimental model of autologous blood-induced intracerebral hemorrhage
KS Jadaun, S Mehan, A Sharma, EM Siddiqui… - Current medical …, 2022 - Springer
Objective Intracerebral hemorrhage (ICH) refers to predominant, sporadic, and non-
traumatic bleeding in the brain parenchyma. The PI3K/AKT/mTOR signaling pathway is an …
traumatic bleeding in the brain parenchyma. The PI3K/AKT/mTOR signaling pathway is an …
[HTML][HTML] Effect of alpha-mangostin in the prevention of behavioural and neurochemical defects in methylmercury-induced neurotoxicity in experimental rats
Methylmercury (MeHg+) is a known neurotoxin that causes progressive motor neuron
degeneration in the central nervous system. Axonal degeneration, oligodendrocyte …
degeneration in the central nervous system. Axonal degeneration, oligodendrocyte …
Melatonin-mediated IGF-1/GLP-1 activation in experimental OCD rats: evidence from CSF, blood plasma, brain and in-silico investigations
Obsessive-compulsive disorder (OCD) is a neuropsychiatric condition characterized by
intrusive, repetitive thoughts and behaviors. Our study uses a validated 8-OH-DPAT-induced …
intrusive, repetitive thoughts and behaviors. Our study uses a validated 8-OH-DPAT-induced …
Forskolin, an Adenylcyclase/cAMP/CREB signaling activator restoring myelin-associated oligodendrocyte destruction in experimental ethidium bromide model of …
Multiple sclerosis (MS) is a chronic neurodegenerative disease marked by oligodendrocyte
loss, which results in central neuronal demyelination. AC/cAMP/CREB signaling …
loss, which results in central neuronal demyelination. AC/cAMP/CREB signaling …
[HTML][HTML] Inhibition of c-JNK/p38MAPK signaling pathway by Apigenin prevents neurobehavioral and neurochemical defects in ethidium bromide-induced experimental …
A Singh, S Upadhayay, S Mehan - Phytomedicine Plus, 2021 - Elsevier
Background Multiple sclerosis (MS) is an idiopathic and autoimmune-mediated
neurodegenerative disease that causes demyelination, neuroinflammation, and axonal loss …
neurodegenerative disease that causes demyelination, neuroinflammation, and axonal loss …
Beta-boswellic acid reverses 3-nitropropionic acid-induced molecular, mitochondrial, and histopathological defects in experimental rat model of Huntington's disease
Huntington's disease (HD) is distinguished by a triple repeat of CAG in exon 1, an increase
in poly Q in the Htt gene, and a loss of GABAergic medium spiny neurons (MSN) in the …
in poly Q in the Htt gene, and a loss of GABAergic medium spiny neurons (MSN) in the …
4-hydroxyisoleucine mediated IGF-1/GLP-1 signalling activation prevents propionic acid-induced autism-like behavioural phenotypes and neurochemical defects in …
Autism is a neuropsychiatric disorder characterized by a neurotransmitter imbalance that
impairs neurodevelopment processes. Autism development is marked by communication …
impairs neurodevelopment processes. Autism development is marked by communication …