[HTML][HTML] CD4 TRM Cells Following Infection and Immunization: Implications for More Effective Vaccine Design
The induction of immunological memory, which is mediated by memory T and B cells, is
central to adaptive protective immunity to pathogens induced by previous infection and is the …
central to adaptive protective immunity to pathogens induced by previous infection and is the …
Chlamydia trachomatis vaccines for genital infections: where are we and how far is there to go?
LM de la Maza, TL Darville, S Pal - Expert review of vaccines, 2021 - Taylor & Francis
Introduction Chlamydia trachomatis is the most common sexually transmitted bacterial
pathogen in the world. Antibiotic treatment does not prevent against reinfection and a …
pathogen in the world. Antibiotic treatment does not prevent against reinfection and a …
Regulation of chlamydial colonization by IFNγ delivered via distinct cells
H Winner, A Friesenhahn, Y Wang, N Stanbury… - Trends in …, 2023 - cell.com
The mouse-adapted pathogen Chlamydia muridarum (CM) induces pathology in the mouse
genital tract but fails to do so in the gastrointestinal tract. CM is cleared from both the genital …
genital tract but fails to do so in the gastrointestinal tract. CM is cleared from both the genital …
Chlamydia trachomatis vaccine development – a view on the current challenges and how to move forward
ÁH Borges, F Follmann, J Dietrich - Expert Review of Vaccines, 2022 - Taylor & Francis
Introduction Chlamydia trachomatis is the most common sexually transmitted bacterial
pathogen in the world. A licensed vaccine is not yet available, but the first vaccines have …
pathogen in the world. A licensed vaccine is not yet available, but the first vaccines have …
Chlamydia overcomes multiple gastrointestinal barriers to achieve long-lasting colonization
G Zhong - Trends in microbiology, 2021 - cell.com
Chlamydia trachomatis (CT) is frequently detected in the human gastrointestinal (GI) tract
despite its leading role in sexually transmitted bacterial infections in the genital tract …
despite its leading role in sexually transmitted bacterial infections in the genital tract …
Chlamydia spreading from the genital tract to the gastrointestinal tract–a two-hit hypothesis
G Zhong - Trends in microbiology, 2018 - cell.com
Chlamydia trachomatis, a leading bacterial cause of sexually transmitted infection-induced
infertility, is frequently detected in the gastrointestinal tract. Chlamydia muridarum, a model …
infertility, is frequently detected in the gastrointestinal tract. Chlamydia muridarum, a model …
[HTML][HTML] Innate Lymphoid Cells in Response to Intracellular Pathogens: Protection Versus Immunopathology
AA Korchagina, E Koroleva… - Frontiers in Cellular and …, 2021 - frontiersin.org
Innate lymphoid cells (ILCs) are a heterogeneous group of cytokine-producing lymphocytes
which are predominantly located at mucosal barrier surfaces, such as skin, lungs, and …
which are predominantly located at mucosal barrier surfaces, such as skin, lungs, and …
IL-23 receptor signaling licenses group 3-like innate lymphoid cells to restrict a live-attenuated oral Chlamydia vaccine in the gut
Y He, Y Wang, R He, AM Abdelsalam… - Infection and …, 2023 - Am Soc Microbiol
An IFNγ-susceptible mutant of Chlamydia muridarum is attenuated in pathogenicity in the
genital tract and was recently licensed as an intr acellular O ral vaccine v ector or intrOv …
genital tract and was recently licensed as an intr acellular O ral vaccine v ector or intrOv …
Preclinical screen for protection efficacy of chlamydial antigens that are immunogenic in humans
C Lu, J Wang, G Zhong - Infection and immunity, 2023 - Am Soc Microbiol
To search for subunit vaccine candidates, immunogenic chlamydial antigens identified in
humans were evaluated for protection against both infection and pathology in a mouse …
humans were evaluated for protection against both infection and pathology in a mouse …
Engineering Vaccines for Tissue‐Resident Memory T Cells
FC Knight, JT Wilson - Advanced therapeutics, 2021 - Wiley Online Library
In recent years, tissue‐resident memory T cells (TRM) have attracted significant attention in
the field of vaccine development. Distinct from central and effector memory T cells, TRM cells …
the field of vaccine development. Distinct from central and effector memory T cells, TRM cells …