[HTML][HTML] The evolution of SARS-CoV-2

PV Markov, M Ghafari, M Beer, K Lythgoe… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …

The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2

L Bauer, BM Laksono, FMS de Vrij, SA Kushner… - Trends in …, 2022 - cell.com
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection is associated with
a diverse spectrum of neurological complications during the acute and postacute stages …

[HTML][HTML] An early warning system for emerging SARS-CoV-2 variants

L Subissi, A von Gottberg, L Thukral, N Worp… - Nature medicine, 2022 - nature.com
An early warning system for emerging SARS-CoV-2 variants | Nature Medicine Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

[PDF][PDF] The T-cell-directed vaccine BNT162b4 encoding conserved non-spike antigens protects animals from severe SARS-CoV-2 infection

CM Arieta, YJ Xie, DA Rothenberg, H Diao, D Harjanto… - Cell, 2023 - cell.com
T cell responses play an important role in protection against beta-coronavirus infections,
including SARS-CoV-2, where they associate with decreased COVID-19 disease severity …

[HTML][HTML] Accelerating antiviral drug discovery: lessons from COVID-19

A von Delft, MD Hall, AD Kwong, LA Purcell… - Nature Reviews Drug …, 2023 - nature.com
During the coronavirus disease 2019 (COVID-19) pandemic, a wave of rapid and
collaborative drug discovery efforts took place in academia and industry, culminating in …

[HTML][HTML] Animal models for COVID-19: advances, gaps and perspectives

C Fan, Y Wu, X Rui, Y Yang, C Ling, S Liu… - … and Targeted Therapy, 2022 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, is the most consequential pandemic of this
century. Since the outbreak in late 2019, animal models have been playing crucial roles in …

[HTML][HTML] Vaccine-associated enhanced disease and pathogenic human coronaviruses

C Gartlan, T Tipton, FJ Salguero, Q Sattentau… - Frontiers in …, 2022 - frontiersin.org
Vaccine-associated enhanced disease (VAED) is a difficult phenomenon to define and can
be confused with vaccine failure. Using studies on respiratory syncytial virus (RSV) …

[HTML][HTML] Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper

CV Sørensen, J Fernández, AC Adams… - Nature …, 2024 - nature.com
Improved therapies are needed against snakebite envenoming, which kills and permanently
disables thousands of people each year. Recently developed neutralizing monoclonal …

[HTML][HTML] Adverse outcomes in SARS-CoV-2–infected pregnant mice are gestational age–dependent and resolve with antiviral treatment

PS Creisher, JL Perry, W Zhong, J Lei… - The Journal of …, 2023 - Am Soc Clin Investig
SARS-CoV-2 infection during pregnancy is associated with severe COVID-19 and adverse
fetal outcomes, but the underlying mechanisms remain poorly understood. Moreover, clinical …

Comparative Pathogenesis of Severe Acute Respiratory Syndrome Coronaviruses

J Zhang, M Rissmann, T Kuiken… - Annual Review of …, 2024 - annualreviews.org
Over the last two decades the world has witnessed the global spread of two genetically
related highly pathogenic coronaviruses, severe acute respiratory syndrome coronavirus …