Osteoporosis is becoming a major concern in the field of public health. The process of bone
loss is insidious and does not directly induce obvious symptoms. Complications indicate an …

Purpose Bone diseases account for an enormous cost burden on health systems. Bone
disorders are considered as age-dependent diseases. The aging of world population has …

Melatonin is an important endogenous hormone that modulates homeostasis in the
microenvironment. Recent studies have indicated that serum melatonin levels are closely …

Increasing bone resorption followed by decreasing bone mineralization are hallmarks of
bone degeneration, which mostly occurs in the elderly population and post-menopausal …

Osteoporosis is a widespread systemic disease characterized by a decrease in bone mass
and an imbalance of the microarchitecture of bone tissue. Experimental and clinical studies …

Objective To explore the difference in the protective effects of intraperitoneal injection of
exogenous melatonin of daytime or nighttime on bone loss in ovariectomized (OVX) rats …

The widespread use of therapeutic glucocorticoids has increased the incidences of
glucocorticoid‐induced osteoporosis (GIOP). Oxidative stress and mitochondrial dysfunction …

Mitochondria plays a role in cell differentiation and apoptosis processes. Maintaining
mitochondrial function is critical, and this involves various aspects of mitochondrial quality …

It was found recently that iron overload can cause osteoporosis in rats. Through in vitro and
in vivo experimentations, the purpose of the present study was to validate and confirm the …

SIRT3 is an NAD+-dependent deacetylase in the mitochondria with an extensive ability to
regulate mitochondrial morphology and function. It has been reported that SIRT3 …