Overexpression of a Gene Encoding a Cytochrome P450, CYP78A9, Induces Large and Seedless Fruit in Arabidopsis
T Ito, EM Meyerowitz - The Plant Cell, 2000 - academic.oup.com
An activation tagging screen in which the cauliflower mosaic virus 35S enhancer was
inserted randomly into an Arabidopsis genome homozygous for the floral homeotic mutation …
inserted randomly into an Arabidopsis genome homozygous for the floral homeotic mutation …
Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus
JK Yano, LS Koo, DJ Schuller, H Li… - Journal of Biological …, 2000 - ASBMB
The structure of the first P450 identified in Archaea, CYP119 from Sulfolobus solfataricus,
has been solved in two different crystal forms that differ by the ligand (imidazole or 4 …
has been solved in two different crystal forms that differ by the ligand (imidazole or 4 …
Fungal cytochrome P450 database
Background Cytochrome P450 enzymes play critical roles in fungal biology and ecology. To
support studies on the roles and evolution of cytochrome P450 enzymes in fungi based on …
support studies on the roles and evolution of cytochrome P450 enzymes in fungi based on …
Functional expression of eukaryotic cytochrome P450s in yeast
L Jiang, L Huang, J Cai, Z Xu… - Biotechnology and …, 2021 - Wiley Online Library
Cytochrome P450 enzymes (P450s) are a superfamily of heme‐thiolate proteins widely
existing in various organisms. Due to their key roles in secondary metabolism, degradation …
existing in various organisms. Due to their key roles in secondary metabolism, degradation …
A systematic gene expression screen of Caenorhabditis elegans cytochrome P450 genes reveals CYP35 as strongly xenobiotic inducible
R Menzel, T Bogaert, R Achazi - Archives of biochemistry and biophysics, 2001 - Elsevier
The soil nematode Caenorhabditis elegans is one of the simplest animals having the status
of a laboratory model. Its genome contains 80 cytochrome P450 genes (CYP). In order to …
of a laboratory model. Its genome contains 80 cytochrome P450 genes (CYP). In order to …
Integrated analysis of cytochrome P450 gene superfamily in the red flour beetle, Tribolium castaneum
Background The functional and evolutionary diversification of insect cytochrome P450s
(CYPs) shaped the success of insects. CYPs constitute one of the largest and oldest gene …
(CYPs) shaped the success of insects. CYPs constitute one of the largest and oldest gene …
Engraftment of human induced pluripotent stem cell-derived hepatocytes in immunocompetent mice via 3D co-aggregation and encapsulation
Cellular therapies for liver diseases and in vitro models for drug testing both require
functional human hepatocytes (Hum-H), which have unfortunately been limited due to the …
functional human hepatocytes (Hum-H), which have unfortunately been limited due to the …
P450 monooxygenases (P450ome) of the model white rot fungus Phanerochaete chrysosporium
Phanerochaete chrysosporium, the model white rot fungus, has been the focus of research
for the past about four decades for understanding the mechanisms and processes of …
for the past about four decades for understanding the mechanisms and processes of …
Mechanisms of inhibitory and regulatory effects of methylenedioxyphenyl compounds on cytochrome P450-dependent drug oxidation
M Murray - Current drug metabolism, 2000 - ingentaconnect.com
Cytochrome P450 (CYP) enzymes catalyse the oxidative conversion of drugs and other
lipophilic compounds to hydrophilic metabolites. Thus, CYPs play a dominant role in the …
lipophilic compounds to hydrophilic metabolites. Thus, CYPs play a dominant role in the …
Cytochrome P450 in the brain; a review
E Hedlund, JA Gustafsson… - Current drug metabolism, 2001 - ingentaconnect.com
After many frustrating decades of unsuccessful attempts to characterize the isoforms of P450
in the brain, several scientific breakthroughs in the 80s and 90s have resulted in major …
in the brain, several scientific breakthroughs in the 80s and 90s have resulted in major …