CRISPR/Cas systems towards next-generation biosensing

Y Li, S Li, J Wang, G Liu - Trends in biotechnology, 2019 - cell.com
Beyond its remarkable genome editing ability, the CRISPR/Cas9 effector has also been
utilized in biosensing applications. The recent discovery of the collateral RNA cleavage …

[HTML][HTML] Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants

SSA Zaidi, A Mahas, H Vanderschuren, MM Mahfouz - Genome biology, 2020 - Springer
To meet increasing global food demand, breeders and scientists aim to improve the yield
and quality of major food crops. Plant diseases threaten food security and are expected to …

Loss of function of a DMR6 ortholog in tomato confers broad-spectrum disease resistance

DPT Thomazella, K Seong… - Proceedings of the …, 2021 - National Acad Sciences
Plant diseases are among the major causes of crop yield losses around the world. To confer
disease resistance, conventional breeding relies on the deployment of single resistance (R) …

[HTML][HTML] Mutations introduced in susceptibility genes through CRISPR/Cas9 genome editing confer increased late blight resistance in potatoes

NP Kieu, M Lenman, ES Wang, BL Petersen… - Scientific Reports, 2021 - nature.com
The use of pathogen-resistant cultivars is expected to increase yield and decrease fungicide
use in agriculture. However, in potato breeding, increased resistance obtained via …

Molecular and genetic bases of heat stress responses in crop plants and breeding for increased resilience and productivity

M Janni, M Gullì, E Maestri, M Marmiroli… - Journal of …, 2020 - academic.oup.com
To ensure the food security of future generations and to address the challenge of the 'no
hunger zone'proposed by the FAO (Food and Agriculture Organization), crop production …

CRISPR technology is revolutionizing the improvement of tomato and other fruit crops

T Wang, H Zhang, H Zhu - Horticulture research, 2019 - academic.oup.com
Fruits are major sources of essential nutrients and serve as staple foods in some areas of
the world. The increasing human population and changes in climate experienced worldwide …

Future of bacterial disease management in crop production

A Sharma, P Abrahamian, R Carvalho… - Annual Review of …, 2022 - annualreviews.org
Bacterial diseases are a constant threat to crop production globally. Current management
strategies rely on an array of tactics, including improved cultural practices; application of …

A detailed landscape of CRISPR-Cas-mediated plant disease and pest management

S Karmakar, P Das, D Panda, K Xie, MJ Baig, KA Molla - Plant Science, 2022 - Elsevier
Genome editing technology has rapidly evolved to knock-out genes, create targeted genetic
variation, install precise insertion/deletion and single nucleotide changes, and perform large …

Exploiting broad-spectrum disease resistance in crops: from molecular dissection to breeding

W Li, Y Deng, Y Ning, Z He… - Annual review of plant …, 2020 - annualreviews.org
Plant diseases reduce crop yields and threaten global food security, making the selection of
disease-resistant cultivars a major goal of crop breeding. Broad-spectrum resistance (BSR) …

[HTML][HTML] Inactivation of a wheat protein kinase gene confers broad-spectrum resistance to rust fungi

N Wang, C Tang, X Fan, M He, P Gan, S Zhang, Z Hu… - Cell, 2022 - cell.com
Wheat crops are frequently devastated by pandemic stripe rust caused by Puccinia
striiformis f. sp. tritici (Pst). Here, we identify and characterize a wheat receptor-like …