T lymphocytes and testicular immunity: a new insight into immune regulation in testes

J Gong, Q Zeng, D Yu, YG Duan - International journal of molecular …, 2020 - mdpi.com
The immune privilege of the testes is necessary to prevent immune attacks to gamete-
specific antigens and paternal major histocompatibility complex (MHC) antigens, allowing …

Microbiology and immune mechanisms associated with male infertility

J Chen, J Chen, Y Fang, Q Shen, K Zhao… - Frontiers in …, 2023 - frontiersin.org
Up to 50% of infertility is caused by the male side. Varicocele, orchitis, prostatitis,
oligospermia, asthenospermia, and azoospermia are common causes of impaired male …

Diabetes mellitus and infertility: different pathophysiological effects in type 1 and type 2 on sperm function

RA Condorelli, S La Vignera, LM Mongioì… - Frontiers in …, 2018 - frontiersin.org
Although the prevalence of sub-infertility in diabetic patients in childbearing age is known,
the mechanisms by which diabetes mellitus (DM) causes male infertility are not completely …

Aberrant gene expression profiling in men with Sertoli cell-only syndrome

T Chen, Y Wang, L Tian, X Guo, J Xia, Z Wang… - Frontiers in …, 2022 - frontiersin.org
Sertoli cell-only syndrome (SCOS) is the most severe and common pathological type of non-
obstructive azoospermia. The etiology of SCOS remains largely unknown to date despite a …

Natural killer and NKT cells in the male reproductive tract

YG Duan, J Gong, WSB Yeung, G Haidl… - Journal of Reproductive …, 2020 - Elsevier
Natural killer (NK) cells are important effector lymphocytes that play a pivotal role in the
innate and adaptive immune responses to tumors and viral infection. NKT cells are a …

Evaluation of seminal fluid leukocyte subpopulations in patients with varicocele

LM Mongioì, A Alamo, AE Calogero… - International …, 2020 - journals.sagepub.com
Varicocele is a common cause of sperm damage. Some studies showed higher
concentration of seminal leukocytes in patients with varicocele. The aim of the study was to …

The enigmatic interplay of immune cells and abnormal spermatozoa through Mendelian randomization

F Zheng, S Li, Z Wang, S Xiong, J Liu… - American Journal of …, 2024 - Wiley Online Library
Purpose Abnormal spermatozoa significantly impact reproductive health, affecting fertility
rates, potentially prolonging conception time, and increasing the risk of miscarriages. This …

Male accessory gland inflammation prevalence in type 2 diabetic patients with symptoms possibly reflecting autonomic neuropathy

RA Condorelli, E Vicari, AE Calogero… - Asian Journal of …, 2014 - journals.lww.com
Male accessory gland inflammation or infection (MAGI) is a potentially underdiagnosed
complication of type 2 diabetes (DM2); specifically, we reported in a recent study that the …

Novel underlying genetic markers for asthenozoospermia due to abnormal spermatogenesis and reproductive organ inflammation

Y Zhang, Y Peng, Y Wang, J Xu… - Experimental and …, 2024 - spandidos-publications.com
Asthenozoospermia, a male fertility disorder, has a complex and multifactorial etiology.
Moreover, the effectiveness of different treatments for asthenozoospermia remains …

Leucocyte subpopulations in the seminal plasma and their effects on fertilisation rates in an IVF cycle

S Seshadri, B Flanagan, G Vince, DI Lewis Jones - Andrologia, 2012 - Wiley Online Library
Controversy exists on the role of leucocytospermia on fertilisation rates and IVF outcomes.
The aim of our study was to identify the effect of leucocytes and leucocyte subpopulations on …