Synergistic psychedelic-NMDAR modulator treatment for neuropsychiatric disorders

U Heresco-Levy, B Lerer - Molecular Psychiatry, 2024 - nature.com
Modern research data suggest a therapeutic role for serotonergic psychedelics in
depression and other neuropsychiatric disorders, although psychotomimetic effects may limit …

[HTML][HTML] The psychedelic future of post-traumatic stress disorder treatment

TG Zaretsky, KM Jagodnik, R Barsic… - Current …, 2024 - ncbi.nlm.nih.gov
Post-traumatic stress disorder (PTSD) is a mental health condition that can occur following
exposure to a traumatic experience. An estimated 12 million US adults are presently affected …

[HTML][HTML] Naturalistic psilocybin use is associated with persisting improvements in mental health and wellbeing: results from a prospective, longitudinal survey

SM Nayak, H Jackson, ND Sepeda, DS Mathai… - Frontiers in …, 2023 - frontiersin.org
Introduction The classic psychedelic psilocybin, found in some mushroom species, has
received renewed interest in clinical research, showing potential mental health benefits in …

[HTML][HTML] Patient perspectives and experiences with psilocybin treatment for treatment-resistant depression: a qualitative study

JJ Breeksema, A Niemeijer, E Krediet, T Karsten… - Scientific reports, 2024 - nature.com
Psilocybin is the most researched classic psychedelic for Treatment-Resistant Depression
(TRD). While optimizing set and setting are considered essential for efficacy and safety …

Assessing potential of psilocybin for depressive disorders

Z Kozak, MW Johnson, ST Aaronson - Expert Opinion on …, 2023 - Taylor & Francis
Introduction There has been increasing interest in the role psilocybin may play in the
treatment of depressive disorders. Several clinical trials have shown psilocybin to have …

Efficacy and safety of psychedelics for the treatment of mental disorders: A systematic review and meta-analysis

Y Yao, D Guo, TS Lu, FL Liu, SH Huang, MQ Diao… - Psychiatry …, 2024 - Elsevier
We aim to systematically review and meta-analyze the effectiveness and safety of
psychedelics [psilocybin, ayahuasca (active component DMT), LSD and MDMA] in treating …

Drug–drug interactions involving classic psychedelics: A systematic review

A Halman, G Kong, J Sarris… - Journal of …, 2024 - journals.sagepub.com
Classic psychedelics, including lysergic acid diethylamide (LSD), psilocybin, mescaline, N,
N-dimethyltryptamine (DMT) and 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT), are …

Essentials of informed consent to psychedelic medicine

M Marks, RW Brendel, C Shachar, IG Cohen - JAMA psychiatry, 2024 - jamanetwork.com
Importance Interest in administering psychedelic agents as mental health treatment is
growing rapidly. As drugmakers invest in developing psychedelic medicines for several …

[HTML][HTML] Ethnoracial inclusion in clinical trials of psychedelics: a systematic review

ME Hughes, A Garcia-Romeu - EClinicalMedicine, 2024 - thelancet.com
Background Prior data indicate limited ethnoracial diversity in studies testing psychedelic-
assisted treatments. Regulatory approval for psychedelic treatments may be imminent given …

Effects of discontinuation of serotonergic antidepressants prior to psilocybin therapy versus escitalopram for major depression

D Erritzoe, T Barba, MJ Spriggs… - Journal of …, 2024 - journals.sagepub.com
Background: There is growing evidence for the therapeutic effects of the psychedelic drug
psilocybin for major depression. However, due to the lack of safety data on combining …