Biomaterial‐based gene therapy

Y Yu, Y Gao, L He, B Fang, W Ge, P Yang, Y Ju… - MedComm, 2023 - Wiley Online Library
Gene therapy, a medical approach that involves the correction or replacement of defective
and abnormal genes, plays an essential role in the treatment of complex and refractory …

[HTML][HTML] CRISPR/Cas9 systems: delivery technologies and biomedical applications

Y Du, Y Liu, J Hu, X Peng, Z Liu - Asian Journal of Pharmaceutical Sciences, 2023 - Elsevier
The emergence of the clustered regularly interspaced short palindromic repeats
(CRISPR)/CRISPR-associated protein 9 (Cas9) genome-editing system has brought about a …

[HTML][HTML] CRISPR/Cas9 system: a reliable and facile genome editing tool in modern biology

D Javaid, SY Ganie, YA Hajam, MS Reshi - Molecular Biology Reports, 2022 - Springer
Genome engineering has always been a versatile technique in biological research and
medicine, with several applications. In the last several years, the discovery of Clustered …

Extracellular vesicles as a potential delivery platform for CRISPR-Cas based therapy in epithelial ovarian cancer

N Godbole, A Quinn, F Carrion, E Pelosi… - Seminars in Cancer …, 2023 - Elsevier
Ovarian Cancer (OC) is the most common gynaecological malignancy and the eighth most
diagnosed cancer in females worldwide. Presently, it ranks as the fifth leading cause of …

Shaping the future from the small scale: dry powder inhalation of CRISPR-Cas9 lipid nanoparticles for the treatment of lung diseases

SP Carneiro, A Greco, E Chiesa, I Genta… - Expert opinion on drug …, 2023 - Taylor & Francis
Introduction Most lung diseases are serious conditions resulting from genetic and
environmental causes associated with high mortality and severe symptoms. Currently …

How to detect CRISPR with CRISPR–employing SHERLOCK for doping control purposes

A Paßreiter, N Naumann, A Thomas, N Grogna… - Analyst, 2022 - pubs.rsc.org
The clustered regularly interspaced short palindromic repeats/CRISPR-associated
(CRISPR/Cas) tool kit constitutes one of today's most frequently used gene editing …

Antimicrobial resistance expansion in pathogens: a review of current mitigation strategies and advances towards innovative therapy

MA Adefisoye, AO Olaniran - JAC-Antimicrobial Resistance, 2023 - academic.oup.com
The escalating problem of antimicrobial resistance (AMR) proliferation in clinically important
pathogens has become one of the biggest threats to human health and the global economy …

[HTML][HTML] Applications of CRISPR Technology to Breast Cancer and Triple Negative Breast Cancer Research

M Pont, M Marqués, MA Sorolla, E Parisi, I Urdanibia… - Cancers, 2023 - mdpi.com
Simple Summary The technique of Clustered Regularly Interspaced Short Palindromic
Repeats (CRISPR) has revolutionised cancer research, including breast cancer and triple …

[HTML][HTML] Nanoformulation of Peptides for Pharmaceutical Applications: In Vitro and In Vivo Perspectives

BR Thimmiah, BTC Chien, KS Fui, LS Yon… - Applied Sciences, 2022 - mdpi.com
Peptides are short sequences of proteins consisting of two or more amino acids that are
linked by peptide bonds. Peptide-based designs and drug deliveries can offer several …

[HTML][HTML] Biomaterial-Based CRISPR/Cas9 Delivery Systems for Tumor Treatment

M Li, F Chen, Q Yang, Q Tang, Z Xiao, X Tong… - Biomaterials …, 2024 - spj.science.org
CRISPR/Cas9 gene editing technology is characterized by high specificity and efficiency,
and has been applied to the treatment of human diseases, especially tumors involving …