Muscular exercise requires transitions to and from metabolic rates often exceeding an order
of magnitude above resting and places prodigious demands on the oxidative machinery and …

Evidence-based recommendations on the clinical use of cardiopulmonary exercise testing
(CPET) in lung and heart disease are presented, with reference to the assessment of …

Effective management of dyspnea in chronic obstructive pulmonary disease (COPD)
requires a clearer understanding of its underlying mechanisms. This roundtable reviews …

Despite its crucial importance, scientists interested in the limitations of human physical
performance have only just started to give the field of oxygen uptake kinetics the attention it …

Exercise testing is increasingly utilized to evaluate the level of exercise intolerance in
patients with lung and heart diseases. Cardiopulmonary exercise testing (CPET) is …

For exercise modalities such as cycling which recruit a substantial muscle mass, muscle
oxygen uptake (V̇O 2) is the primary determinant of pulmonary V̇O 2. Indeed, the kinetic …

Background Patients with idiopathic pulmonary fibrosis (IPF) have severely limited exercise
capacity due to dyspnea, hypoxemia, and abnormal lung mechanics. This pilot study was …

Background Exercise training within the context of pulmonary rehabilitation improves
outcomes of exercise capacity, dyspnea and health‐related quality of life in individuals with …

ABSTRACT HOFF, J., AE TJKNNA, S. STEINSHAMN, M. HKYDAL, RS RICHARDSON, and
J. HELGERUD. Maximal Strength Training of the Legs in COPD: A Therapy for Mechanical …

Study objectives The slow oxygen uptake (V˙ o 2) kinetics observed in COPD patients is a
manifestation of skeletal muscle dysfunction of multifactorial origin. We determined whether …