Medical interventions for primary open angle glaucoma and ocular hypertension

C Vass, C Hirn, T Sycha, O Findl… - Cochrane Database …, 2007 - cochranelibrary.com
Background Primary open angle glaucoma (POAG) is a progressive optic neuropathy with
an elevated intraocular pressure (IOP), where the optic nerve head becomes pathologically …

Current primary open-angle glaucoma treatments and future directions

G Beidoe, SA Mousa - Clinical Ophthalmology, 2012 - Taylor & Francis
Primary open-angle glaucoma (POAG) is a leading cause of blindness with no known cure.
Management of the disease focuses on lowering intraocular pressure (IOP) with current …

Antiglaucoma medications: a review of safety and tolerability issues related to their use

JS Schuman - Clinical therapeutics, 2000 - Elsevier
BACKGROUND: Much experience has been gained with the use of older classes of
antiglaucoma agents—topical beta-adrenergic-receptor antagonists, nonselective …

Ophthalmic timolol: plasma concentration and systemic cardiopulmonary effects

T Nieminen, T Lehtimäki, J Mäenpää… - … journal of clinical and …, 2007 - Taylor & Francis
Timolol maleate is a non‐selective β‐adrenoceptor antagonist currently used mainly as an
ocular preparation for the treatment of glaucoma and ocular hypertension. Despite the …

Effects of glaucoma medications on the cardiorespiratory and intraocular pressure status of newly diagnosed glaucoma patients

A Waldock, J Snape, CM Graham - British journal of ophthalmology, 2000 - bjo.bmj.com
AIMS To evaluate the short term cardiovascular, respiratory, and intraocular pressure (IOP)
effects of four glaucoma medications in newly diagnosed glaucoma patients. METHODS 141 …

Polymorphisms of genes CYP2D6, ADRB1 and GNAS1 in pharmacokinetics and systemic effects of ophthalmic timolol. A pilot study

T Nieminen, H Uusitalo, J Mäenpää… - European journal of …, 2005 - Springer
Objective To test the hypotheses that (1) CYP2D6 genotype is associated with
pharmacokinetics of ophthalmic timolol and (2) variation in genotypes of ADRB1 (β 1 …

A review of the medical treatment of pediatric glaucomas at Moorfields Eye Hospital

L Chang, EL Ong, C Bunce, J Brookes… - Journal of …, 2013 - journals.lww.com
Purpose: To report on the medical treatments used for pediatric glaucomas. Patients and
Methods: A retrospective case series consisting of reviewing the medical notes of pediatric …

Cardiovascular and respiratory considerations with pharmacotherapy of glaucoma and ocular hypertension

JA Han, WH Frishman, SW Sun, PM Palmiero… - Cardiology in …, 2008 - journals.lww.com
Glaucoma and ocular hypertension are highly prevalent conditions in individuals over the
age of 40 and are commonly seen together in patients with cardiovascular disease. Many of …

Systemic adverse effects of ophthalmic β-blockers

JAV Zanden, RJ Valuck, CL Bunch… - Annals of …, 2001 - journals.sagepub.com
OBJECTIVE: To review published clinical information on the systemic adverse effects of
ophthalmic β-blockers for the purpose of developing a pilot contraindication/warning system …

Topical beta blockers in asthmatic patients–is it safe?

I Kaiserman, A Fendyur, S Vinker - Current Eye Research, 2009 - Taylor & Francis
Purpose: To investigate the use of topical ocular anti-glaucoma medications by
glaucomatous patients with obstructive pulmonary disease and their effect on related …