Persistent lung injury and prothrombotic state in long COVID
M Xiang, H Jing, C Wang, VA Novakovic… - Frontiers in …, 2022 - frontiersin.org
Lung injury may persist during the recovery period of COVID-19 as shown through imaging,
six-minute walk, and lung function tests. The pathophysiological mechanisms leading to …
six-minute walk, and lung function tests. The pathophysiological mechanisms leading to …
Pulmonary drug delivery for acute respiratory distress syndrome
The acute respiratory distress syndrome (ARDS) is a life-threatening condition that causes
respiratory failure. Despite numerous clinical trials, there are no molecularly targeted …
respiratory failure. Despite numerous clinical trials, there are no molecularly targeted …
Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress …
Background Geoeconomic variations in epidemiology, the practice of ventilation, and
outcome in invasively ventilated intensive care unit (ICU) patients without acute respiratory …
outcome in invasively ventilated intensive care unit (ICU) patients without acute respiratory …
Therapeutic strategies to fight COVID‐19: Which is the status artis?
C Scavone, A Mascolo, C Rafaniello… - British Journal of …, 2022 - Wiley Online Library
COVID‐19 is a complex disease, and many difficulties are faced today especially in the
proper choice of pharmacological treatments. The role of antiviral agents for COVID‐19 is …
proper choice of pharmacological treatments. The role of antiviral agents for COVID‐19 is …
Randomized clinical trial of a combination of an inhaled corticosteroid and beta agonist in patients at risk of developing the acute respiratory distress syndrome
E Festic, GE Carr, R Cartin-Ceba, RF Hinds… - Critical care …, 2017 - journals.lww.com
Objectives: Effective pharmacologic treatments directly targeting lung injury in patients with
the acute respiratory distress syndrome are lacking. Early treatment with inhaled …
the acute respiratory distress syndrome are lacking. Early treatment with inhaled …
Statin and aspirin as adjuvant therapy in hospitalised patients with SARS-CoV-2 infection: a randomised clinical trial (RESIST trial)
Background Statins and aspirin have been proposed for treatment of COVID-19 because of
their anti-inflammatory and anti-thrombotic properties. Several observational studies have …
their anti-inflammatory and anti-thrombotic properties. Several observational studies have …
[HTML][HTML] SARS-CoV-2 receptors are expressed on human platelets and the effect of aspirin on clinical outcomes in COVID-19 patients
A Sahai, R Bhandari, M Koupenova… - Research …, 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus disease-2019 (COVID-19) caused by SARS-CoV-2 is an ongoing viral
pandemic marked by increased risk of thrombotic events. However, the role of platelets in …
pandemic marked by increased risk of thrombotic events. However, the role of platelets in …
Platelets as key players in inflammation and infection
L Nicolai, S Massberg - Current opinion in hematology, 2020 - journals.lww.com
New findings highlight the complex interplay of innate immunity, coagulation and platelets in
inflammation and infection, and unravel novel molecular pathways and effector functions …
inflammation and infection, and unravel novel molecular pathways and effector functions …
Designing an ARDS trial for 2020 and beyond: focus on enrichment strategies
LB Ware, MA Matthay, A Mebazaa - Intensive Care Medicine, 2020 - Springer
With the exception of a few successes in trials of supportive care, the majority of
interventional clinical trials for acute respiratory distress syndrome (ARDS) have not led to …
interventional clinical trials for acute respiratory distress syndrome (ARDS) have not led to …
Effect of aspirin on short-term outcomes in hospitalized patients with COVID-19
A Sahai, R Bhandari, M Godwin, T McIntyre… - Vascular …, 2021 - journals.sagepub.com
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 is an ongoing viral
pandemic marked by increased risk of thrombotic events. However, the role of platelets in …
pandemic marked by increased risk of thrombotic events. However, the role of platelets in …