In 1971, Folkman proposed that tumors could be limited to very small sizes by blocking
angiogenesis. Angiogenesis is the generation of new blood vessels from pre-existing …

Gastric cancer (GC) is a fatal illness, and its mortality rate is very high all over the world. At
present, it is a serious health problem for any country. It is a multifactorial disease due to the …

Background The rising prevalence of many chronic diseases related to gut barrier
dysfunction coincides with the increased global usage of dietary emulsifiers in recent …

Simple Summary Gastrointestinal (GI) cancers are the leading cancer-related deaths
worldwide. Despite improved survival rates with current treatments, recurrence remains a …

Glucosidase II beta subunit (GluIIß), encoded from PRKCSH, is a subunit of the glucosidase
II enzyme responsible for quality control of N-linked glycoprotein folding and suppression of …

Background and purpose While HCC is an inflammation-associated cancer, CRLM
develops on permissive healthy liver microenvironment. To evaluate the immune aspects of …

The complexity of the tumor microenvironment (TME) is a crucial factor in lung
adenocarcinoma (LUAD) progression. To gain deeper insights into molecular mechanisms …

Background In chronic cystic fibrosis (CF) lung disease, neutrophilic inflammation and T-cell
inhibition occur concomitantly, partly due to neutrophil-mediated release of the T-cell …

Simple Summary Clear cell renal cell carcinoma (ccRCC) is the most common form of renal
cancer. Currently, treatment of metastatic ccRCC (mccRCC) is challenging despite the use …

Background The tumor microenvironment contains chemokines that play a crucial role in
various processes, such as tumorigenesis, inflammation, and therapy resistance, in different …