Objective: To reconstruct the onset date of the HIV-1 B and F epidemics in Brazil based on
virus diversification over time. Design: We studied HIV-1 env V3 sequences (210nt) with a …

The perspective for the development of anti-HIV/AIDS vaccines became a target sought by
several research groups and pharmaceutical companies. However, the complex virus …

We have investigated the phenotypic and genotypic susceptibility of 14 HIV-1 strains
isolated from individuals failing HAART therapy to protease inhibitors (PI). Proviral and …

The emergence of resistance to antiretroviral drugs is a major obstacle to the successful
treatment of human immunodeficiency virus type 1 (HIV-1)-infected patients. In this work, we …

BACKGROUND The human immunodeficiency virus type 1, F1 sub-subtype (HIV-1 F1)
circulates in three continents: Africa, Europe, and South America. In Brazil, this sub-subtype …

Objective: Phylogenetic analysis of gene sequences of HIV-1 has led to the classification of
isolates into a major group (M) of viruses, itself divided into subtypes (A to I), and a minor …

The genetic variation of the human immunodeficiency virus type 1 (HIV-1) protease gene
(prt) permits the classification of HIV-1 strains into five distinct protease subtypes, which …

Because immunologic classification of human immunodeficiency virus type 1 (HIV) might be
more relevant than genotypic classification for designing polyvalent vaccines, studies were …

Background The HIV-1 subtype B epidemic in Brazil is peculiar because of the high
frequency of isolates having the GWGR tetramer at V3 loop region. It has been suggested …

Besides being extremely useful in measuring the level of HIV-1 diversity and prevalence in
populations, the molecular analysis of genomic sequences provides crucial surveillance …