Local anesthetics (LAs) are commonly infiltrated into surgical wounds for postsurgical
analgesia. While many adjuncts to LA agents have been studied, it is unclear which adjuncts …

BACKGROUND The duration of analgesia provided by nerve blocks is limited if local
anaesthetics are administered alone. Therefore, several additives, including …

Abstract Background and Objectives Postoperative pain and stress elicit hormonal changes.
We aimed at comparing the effects of wound infiltration with ketamine versus …

Aims: The aim of this study was to compare the efficacy of local subcutaneous wound
infiltration of ropivacaine alone with ropivacaine plus dexmedetomidine for postoperative …

Aims: The primary objective was to assess whether addition of dexmedetomidine to
bupivacaine prolonged the duration of analgesia. The secondary objective was to compare …

Results: The median time to first rescue analgesia (median; 95% confidence interval [CI]) in
group RD was 930 (854.3 to 1005.7) minutes. This was significantly longer (P= 0.000) than …

Background: Lignocaine+ adrenaline; a local anesthetic agent; frequently used for
perilesional infiltration, maintains the stable hemodynamics and decreases the …

Background Postoperative pain is a major problem, especially in children, as their tolerance
level is lower and several drugs are contraindicated in childhood. This study aimed to …

To further identify the real efficacy and safety of dexmedetomidine as an adjuvant to local
wound infiltration anaesthesia, we conducted this meta‐analysis. The systematic search …

背景: 高龄髋, 膝关节置换中可以选择不同的镇痛方式, 考虑到高龄患者的实际情况,
需要合理地进行麻醉方式选择, 以达到麻醉起效快, 维持时间长以及镇痛效果好等目的. 目的 …