Following the discovery of leptin in 1994, the scientific and clinical communities have held
great hope that manipulation of the leptin axis may lead to the successful treatment of …

Obesity has become an important burden for the health system of industrialized countries
and must be regarded as a serious public health issue in our time. Obesity is associated with …

Hormone-sensitive lipase (HSL) is the predominant lipase effector of catecholamine-
stimulated lipolysis in adipocytes. HSL-dependent lipolysis in response to catecholamines is …

The identification and sequencing of the ob gene and its product, leptin, in late 1994 opened
new insights in the study of the mechanisms controlling body weight and led to a surge of …

Phosphorylation of the lipid droplet-associated protein perilipin A (Peri A) mediates the
actions of cyclic AMP-dependent protein kinase A (PKA) to stimulate triglyceride hydrolysis …

Leptin, the product of the ob gene, is elevated in obese humans and appears to be closely
related to body fat content. The purpose of the present investigation was to determine the …

Objective: To disclose the possible relationship between habitual tea consumption and
changes in total body fat and fat distribution in humans. Research Methods and Procedures …

Advancing age is associated with changes in fat and carbohydrate (CHO) metabolism,
which is considered a risk factor for cardiovascular disease and diabetes. The effects of …

Exercise is a powerful and effective preventive measure against chronic diseases by
increasing energy expenditure and substrate mobilization. Long-duration acute exercise …

Possible nitric oxide (NO)‐mediated effects on lipolysis were investigated in vivo in human
subcutaneous adipose tissue using microdialysis, as well as in vitro on isolated fat cells of …