Role of hemokinin-1 in health and disease

É Borbély, Z Helyes - Neuropeptides, 2017 - Elsevier
Abstract Hemokinin-1 (HK-1), the newest tachykinin encoded by the Tac4 gene was
discovered in 2000. Its name differs from that of the other members of this peptide family due …

[HTML][HTML] Hemokinin-1 gene expression is upregulated in trigeminal ganglia in an inflammatory orofacial pain model: potential role in peripheral sensitization

T Aczél, A Kecskés, J Kun, K Szenthe, F Bánáti… - International journal of …, 2020 - mdpi.com
A large percentage of primary sensory neurons in the trigeminal ganglia (TG) contain
neuropeptides such as tachykinins or calcitonin gene-related peptide. Neuropeptides …

[HTML][HTML] Impact of short and long exposure to cafeteria diet on food intake and white adipose tissue lipolysis mediated by glucagon-like peptide 1 receptor

P Mattar, C Jaque, JA Teske, E Morselli… - Frontiers in …, 2023 - frontiersin.org
Introduction The modern food environment facilitates excessive calorie intake, a major driver
of obesity. Glucagon-like peptide 1 (GLP1) is a neuroendocrine peptide that has been the …

[HTML][HTML] Hemokinin-1 (4-11)-induced analgesia selectively up-regulates δ-opioid receptor expression in mice

CY Fu, RL Xia, TF Zhang, Y Lu, SF Zhang, ZQ Yu, T Jin… - PloS one, 2014 - journals.plos.org
Our previous studies have shown that an active fragment of human tachykinins (hHK-1 (4-
11)) produced an opioid-independent analgesia after intracerebroventricular (icv) injection …

A small interfering RNA targeting vascular endothelial growth factor efficiently inhibits growth of VX2 cells and VX2 tumor model of hepatocellular carcinoma in rabbit …

Y Zou, CG Guo, ZG Yang, JH Sun… - Drug Design …, 2016 - Taylor & Francis
Introduction Hepatocellular carcinoma is currently the second leading cause of cancer-
related deaths worldwide with an increasing incidence. Objective The objective of this study …

Mouse hemokinin-1 decapeptide subjected to a brain-specific post-translational modification

G Deliconstantinos, S Barton, M Soloviev, N Page - in vivo, 2017 - iv.iiarjournals.org
Background/Aim: The tachykinin mouse hemokinin-1, expressed by the mouse Tac4 gene,
produces either analgesia or nociception, interacting with the neurokinin 1 receptor. TAC4 …

Interaction of endokinin A/B and (Mpa6)-γ2-MSH-6–12 in pain regulation in mice

L Zhou, Q Yang, C He, C Wei, Y Yang, S Dong - Neuropeptides, 2015 - Elsevier
The present study focused on the interactive effects of (Mpa 6)-γ2-MSH-6–12 (Mpa, spinal
level) and endokinin A/B (EKA/B, supraspinal level) on pain regulation in mice. EKA/B (30 …

[PDF][PDF] Mechanisms of trigeminal activation and sensitisation: implications for migraine pathophysiology

A Tímea - 2022 - pea.lib.pte.hu
Although activation of the trigeminal system is at the pathophysiological basis of all orofacial
and headache disorders, location, attack frequency, duration, accompanying symptoms, and …

[PDF][PDF] Central distribution sites and protein expression of human HK-1 in mice

HW Zhou, X Wang, Q Chen, CT Ge, Y Shi… - Int J Clin Exp Pathol, 2017 - e-century.us
Human hemokinin-1 (human HK-1) is a member of the mammalian tachykinin family
encoded by Pptc gene, whose biological activities are needed further investigated. In our …

[引用][C] A TRIGEMINÁLIS AKTIVÁCIÓ ÉS SZENZITIZÁCIÓ MECHANIZMUSAI: BETEKINTÉS A MIGRÉN KÓRÉLETTANÁBA

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