[HTML][HTML] Epigenetic regulation of MicroRNA clusters and families during tumor development

J Gregorova, P Vychytilova-Faltejskova, S Sevcikova - Cancers, 2021 - mdpi.com
Simple Summary In this review, the history of RNA interference discovery and current
knowledge about microRNA biogenesis and post-transcriptional regulation of gene …

[HTML][HTML] Extranodal NK/T-cell lymphomas: The role of natural killer cells and EBV in lymphomagenesis

A Saleem, Y Natkunam - International journal of molecular sciences, 2020 - mdpi.com
Natural killer (NK) cells are lymphocytes involved in innate and adaptive immune functions.
They are the presumed cell of origin of distinct hematolymphoid malignancies, including …

miR-654-3p predicts the prognosis of hepatocellular carcinoma and inhibits the proliferation, migration, and invasion of cancer cells

J Yang, Z Zhang, S Chen, W Dou, R Xie… - Cancer …, 2020 - content.iospress.com
BACKGROUND: Increasing evidence reveals that aberrant microRNAs (miRNAs)
expression play a crucial role in the tumorigenesis of cancers, including hepatocellular …

Diffuse large B-cell lymphoma: Time to focus on circulating blood nucleic acids?

G Regazzo, F Marchesi, M Spagnuolo, ABD Méndez… - Blood Reviews, 2021 - Elsevier
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous neoplasm with diverse genetic
abnormalities and outcomes. To date, DLBCL is invasively diagnosed by tissue biopsy and …

Epigenetic regulation of miR-518a-5p-CCR6 feedback loop promotes both proliferation and invasion in diffuse large B cell lymphoma

Q Huang, F Zhang, H Fu, J Shen - Epigenetics, 2021 - Taylor & Francis
To investigate the detailed functions and underlying mechanisms of miR-518a-5p/CCR6 in
diffuse large B cell lymphoma (DLBCL) is needed. In this study, CCR6 expression levels …

[HTML][HTML] Function of Deptor and its roles in hematological malignancies

M Morales-Martinez, A Lichtenstein, MI Vega - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Deptor is a protein that interacts with mTOR and that belongs to the mTORC1 and mTORC2
complexes. Deptor is capable of inhibiting the kinase activity of mTOR. It is well known that …

[HTML][HTML] Метилирование генов р53-респонзивных онкосупрессорных микроРНК при гемобластозах

ЕН Воропаева, ТИ Поспелова… - Сибирский …, 2022 - cyberleninka.ru
Цель исследования-представить современные данные о частоте и значении
метилирования генов ряда р53-респонзивных онкосупрессорных микроРНК при …

The landscape of new drugs in extranodal NK/T-cell lymphoma

L Wang, LR Li, L Zhang, JW Wang - Cancer Treatment Reviews, 2020 - Elsevier
To date, much progress has been made in early-stage extranodal NK/T-cell lymphoma
(ENKTCL), and risk-adapted therapy with radiotherapy (RT) alone for the low-risk group and …

[HTML][HTML] MiRNAs and lncRNAs in NK cell biology and NK/T-cell lymphoma

FX Gao, SR He, AS Jin - Genes & Diseases, 2021 - Elsevier
The important role of lncRNAs and miRNAs in directing immune responses has become
increasingly clear. Recent evidence conforms that miRNAs and lncRNAs are involved in NK …

[HTML][HTML] DNA Methyltransferase Inhibitors Induce Cerebral Dopamine Neurotrophic Factor Expression in C6 Glioma Cells

SZ Mukhtar, LP Niles - American Journal of Molecular Biology, 2023 - scirp.org
Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived
neurotrophic factor (MANF) are involved in neuroprotection and mitigating endoplasmic …