[HTML][HTML] Food-borne chemical carcinogens and the evidence for human cancer risk
Commonly consumed foods and beverages can contain chemicals with reported
carcinogenic activity in rodent models. Moreover, exposures to some of these substances …
carcinogenic activity in rodent models. Moreover, exposures to some of these substances …
[HTML][HTML] Next-generation DNA damage sequencing
Cellular DNA is constantly chemically altered by exogenous and endogenous agents. As all
processes of life depend on the transmission of the genetic information, multiple biological …
processes of life depend on the transmission of the genetic information, multiple biological …
The key characteristics of carcinogens: relationship to the hallmarks of cancer, relevant biomarkers, and assays to measure them
The key characteristics (KC) of human carcinogens provide a uniform approach to
evaluating mechanistic evidence in cancer hazard identification. Refinements to the …
evaluating mechanistic evidence in cancer hazard identification. Refinements to the …
Organophosphate pesticide-induced toxicity through DNA damage and DNA repair mechanisms
J Prathiksha, RK Narasimhamurthy, HS Dsouza… - Molecular Biology …, 2023 - Springer
Organophosphate pesticides (OPs) are widely used in agriculture, healthcare, and other
industries due to their ability to kill pests. However, OPs can also have genotoxic effects on …
industries due to their ability to kill pests. However, OPs can also have genotoxic effects on …
Nose to brain delivery of naringin-loaded chitosan nanoparticles for potential use in oxaliplatin-induced chemobrain in rats: impact on oxidative stress, cGAS/STING …
Objectives Oxaliplatin induces chemobrain in cancer patients/survivors. Nutraceutical
naringin has antioxidant and anti-inflammatory properties with low oral bioavailability. Our …
naringin has antioxidant and anti-inflammatory properties with low oral bioavailability. Our …
Main mechanisms for carcinogenic heterocyclic amine reduction in cooked meat by natural materials
HJ Kang, SY Lee, JH Kang, JH Kim, HW Kim, DH Oh… - Meat Science, 2022 - Elsevier
Carcinogens such as heterocyclic amine (HCA), produced during meat cooking, pose a risk
of digestive and reproductive cancers in humans. Nevertheless, the exact mechanisms for …
of digestive and reproductive cancers in humans. Nevertheless, the exact mechanisms for …
Mass spectrometry analysis of DNA and protein adducts as biomarkers in human exposure to cigarette smoking: acrolein as an example
HJC Chen - Chemical Research in Toxicology, 2023 - ACS Publications
Acrolein is a major component in cigarette smoke and a product of endogenous lipid
peroxidation. It is difficult to distinguish human exposure to acrolein from exogenous sources …
peroxidation. It is difficult to distinguish human exposure to acrolein from exogenous sources …
Precarcinogens in food–Mechanism of action, formation of DNA adducts and preventive measures
B Bukowska, P Duchnowicz, TB Tumer, J Michałowicz… - Food Control, 2023 - Elsevier
Food quality and food composition play key roles in human health. Food may contain
harmful ingredients apart from the basic ingredients beneficial to our body. A harmful group …
harmful ingredients apart from the basic ingredients beneficial to our body. A harmful group …
[HTML][HTML] The relationship between tobacco and breast cancer incidence: A systematic review and meta-analysis of observational studies
Y He, Y Si, X Li, J Hong, C Yu, N He - Frontiers in Oncology, 2022 - frontiersin.org
Background The effect of tobacco on breast cancer (BC) is controversial. The purpose of this
study was to investigate the relationship between tobacco and BC. Methods A search was …
study was to investigate the relationship between tobacco and BC. Methods A search was …
[HTML][HTML] Mechanisms of E-Cigarette Vape-Induced Epithelial Cell Damage
E Auschwitz, J Almeda, CD Andl - Cells, 2023 - mdpi.com
E-cigarette use has been reported to affect cell viability, induce DNA damage, and modulate
an inflammatory response resulting in negative health consequences. Most studies focus on …
an inflammatory response resulting in negative health consequences. Most studies focus on …