Breast cancer (BC) is the most common malignancy responsible for the largest number of
deaths in women worldwide. The risk of developing BC is predisposed by many factors such …

Recently, advances in molecular biology and bioinformatics have allowed a more thorough
understanding of tumorigenesis in aggressive PitNETs (pituitary neuroendocrine tumors) …

VEGF/VEGFR signal axis has been proven to be an important target for development of
novel cancer therapies. One challenging aspect in small molecular VEGFR inhibitors is to …

Dysfunction of the lymphatic system is associated with a wide range of disease phenotypes.
The restoration of dysfunctional lymphatic vessels has been hypothesized as an innovative …

基质金属蛋白酶(matrix metallopeptidase, MMPs) 家族是一类锌依赖性内肽酶,
可降解大多数细胞外基质. MT1-MMP 是MMPs 家族的重要成员, 定位在细胞膜上 …

Cancer invasion and metastasis remain the major causes of over 90% of patient deaths.
Molecular imaging methods such as computed tomography (CT)/magnetic resonance …

Pituitary adenomas (PAs) are noncancerous tumors, and about 35% of those reported to be
invasive have been classified as “invasive pituitary adenomas (IPAs)”. In clinical, operative …

Breast cancer is the most common malignancy in women globally. The increasing worldwide
incidence of this type of cancer illustrates the challenge it represents for healthcare …

Matrix metalloproteinases have a broad spectrum of substrates ranging from extracellular
matrix components and adhesion molecules to chemokines and growth factors. Despite …

Background: Vascular endothelial growth factor (VEGF) has an essential role in tumor
metastasis by inducing the construction of abnormal blood vessels. Epidermal growth factor …